{"binder_interface_residues":[{"auth_chain_id":"C","author_residue_number":"8","contacting_atom_pair_count":1,"contacting_partner_residue_count":1,"insertion_code":null,"nearest_distance_angstrom":4.3173,"residue_name":"VAL"},{"auth_chain_id":"C","author_residue_number":"10","contacting_atom_pair_count":93,"contacting_partner_residue_count":9,"insertion_code":null,"nearest_distance_angstrom":3.1597,"residue_name":"ARG"},{"auth_chain_id":"C","author_residue_number":"11","contacting_atom_pair_count":25,"contacting_partner_residue_count":4,"insertion_code":null,"nearest_distance_angstrom":3.3459,"residue_name":"GLY"},{"auth_chain_id":"C","author_residue_number":"12","contacting_atom_pair_count":133,"contacting_partner_residue_count":10,"insertion_code":null,"nearest_distance_angstrom":2.7561,"residue_name":"ASP"},{"auth_chain_id":"C","author_residue_number":"13","contacting_atom_pair_count":25,"contacting_partner_residue_count":7,"insertion_code":null,"nearest_distance_angstrom":3.7952,"residue_name":"LEU"},{"auth_chain_id":"C","author_residue_number":"15","contacting_atom_pair_count":33,"contacting_partner_residue_count":4,"insertion_code":null,"nearest_distance_angstrom":3.5484,"residue_name":"GLU"},{"auth_chain_id":"C","author_residue_number":"16","contacting_atom_pair_count":39,"contacting_partner_residue_count":6,"insertion_code":null,"nearest_distance_angstrom":3.6506,"residue_name":"LEU"},{"auth_chain_id":"C","author_residue_number":"17","contacting_atom_pair_count":3,"contacting_partner_residue_count":2,"insertion_code":null,"nearest_distance_angstrom":4.8397,"residue_name":"MET"},{"auth_chain_id":"C","author_residue_number":"19","contacting_atom_pair_count":9,"contacting_partner_residue_count":1,"insertion_code":null,"nearest_distance_angstrom":2.9302,"residue_name":"ARG"},{"auth_chain_id":"C","author_residue_number":"20","contacting_atom_pair_count":2,"contacting_partner_residue_count":1,"insertion_code":null,"nearest_distance_angstrom":4.5343,"residue_name":"ALA"},{"auth_chain_id":"C","author_residue_number":"39","contacting_atom_pair_count":16,"contacting_partner_residue_count":2,"insertion_code":null,"nearest_distance_angstrom":3.5451,"residue_name":"ASN"},{"auth_chain_id":"C","author_residue_number":"41","contacting_atom_pair_count":7,"contacting_partner_residue_count":1,"insertion_code":null,"nearest_distance_angstrom":3.6061,"residue_name":"LYS"},{"auth_chain_id":"C","author_residue_number":"63","contacting_atom_pair_count":29,"contacting_partner_residue_count":3,"insertion_code":null,"nearest_distance_angstrom":2.6586,"residue_name":"ARG"},{"auth_chain_id":"C","author_residue_number":"64","contacting_atom_pair_count":9,"contacting_partner_residue_count":1,"insertion_code":null,"nearest_distance_angstrom":3.642,"residue_name":"PHE"},{"auth_chain_id":"C","author_residue_number":"65","contacting_atom_pair_count":7,"contacting_partner_residue_count":2,"insertion_code":null,"nearest_distance_angstrom":3.9729,"residue_name":"PRO"},{"auth_chain_id":"C","author_residue_number":"66","contacting_atom_pair_count":47,"contacting_partner_residue_count":6,"insertion_code":null,"nearest_distance_angstrom":3.4168,"residue_name":"ARG"}],"claim_ceiling":"observed heavy-atom contact geometry in the deposited coordinate model","counts":{"binder_chain_count":1,"binder_interface_residue_count":16,"binder_polymer_residue_count":72,"residue_contact_pair_count":60,"target_chain_count":2,"target_interface_residue_count":33,"target_polymer_residue_count":682},"created_at":"2026-09-04","evidence_class":"experimental-reference-binder-interface","interface_id":"IF-RCSB-8TCG-AB-C","prepared_artifacts":{"residue_map":{"bytes":22299,"sha256":"f4ea4b7d1918716e97d8ca5bba8649be05b7864003f87e009ca16d1c84694f9c"},"target_only_pdb":{"bytes":426960,"sha256":"d75553018fdedd33abb9e97015ad88773eef30b5f79944590d95db97e78cc1ec"}},"recommended_design_hotspots":{"eligible_target_auth_chain_ids":["B"],"requested_count":10,"residues":[{"auth_chain_id":"B","author_residue_number":"183","contacting_atom_pair_count":39,"contacting_partner_residue_count":6,"insertion_code":null,"nearest_binder_contact":{"atom_name":"NH1","auth_chain_id":"C","author_residue_number":"63","distance_angstrom":2.6586,"insertion_code":null,"residue_name":"ARG"},"nearest_distance_angstrom":2.6586,"recommended_target_atom":"O","residue_name":"ILE"},{"auth_chain_id":"B","author_residue_number":"126","contacting_atom_pair_count":39,"contacting_partner_residue_count":4,"insertion_code":null,"nearest_binder_contact":{"atom_name":"OD2","auth_chain_id":"C","author_residue_number":"12","distance_angstrom":2.7561,"insertion_code":null,"residue_name":"ASP"},"nearest_distance_angstrom":2.7561,"recommended_target_atom":"N","residue_name":"ALA"},{"auth_chain_id":"B","author_residue_number":"219","contacting_atom_pair_count":18,"contacting_partner_residue_count":4,"insertion_code":null,"nearest_binder_contact":{"atom_name":"N","auth_chain_id":"C","author_residue_number":"12","distance_angstrom":2.9783,"insertion_code":null,"residue_name":"ASP"},"nearest_distance_angstrom":2.9783,"recommended_target_atom":"O","residue_name":"ILE"},{"auth_chain_id":"B","author_residue_number":"129","contacting_atom_pair_count":17,"contacting_partner_residue_count":3,"insertion_code":null,"nearest_binder_contact":{"atom_name":"NH1","auth_chain_id":"C","author_residue_number":"19","distance_angstrom":2.9302,"insertion_code":null,"residue_name":"ARG"},"nearest_distance_angstrom":2.9302,"recommended_target_atom":"OD2","residue_name":"ASP"},{"auth_chain_id":"B","author_residue_number":"221","contacting_atom_pair_count":16,"contacting_partner_residue_count":3,"insertion_code":null,"nearest_binder_contact":{"atom_name":"CA","auth_chain_id":"C","author_residue_number":"11","distance_angstrom":3.6279,"insertion_code":null,"residue_name":"GLY"},"nearest_distance_angstrom":3.6279,"recommended_target_atom":"OG1","residue_name":"THR"},{"auth_chain_id":"B","author_residue_number":"218","contacting_atom_pair_count":36,"contacting_partner_residue_count":2,"insertion_code":null,"nearest_binder_contact":{"atom_name":"OD2","auth_chain_id":"C","author_residue_number":"12","distance_angstrom":3.1197,"insertion_code":null,"residue_name":"ASP"},"nearest_distance_angstrom":3.1197,"recommended_target_atom":"N","residue_name":"ASN"},{"auth_chain_id":"B","author_residue_number":"127","contacting_atom_pair_count":33,"contacting_partner_residue_count":2,"insertion_code":null,"nearest_binder_contact":{"atom_name":"OD1","auth_chain_id":"C","author_residue_number":"12","distance_angstrom":2.9572,"insertion_code":null,"residue_name":"ASP"},"nearest_distance_angstrom":2.9572,"recommended_target_atom":"N","residue_name":"SER"},{"auth_chain_id":"B","author_residue_number":"316","contacting_atom_pair_count":20,"contacting_partner_residue_count":2,"insertion_code":null,"nearest_binder_contact":{"atom_name":"OD1","auth_chain_id":"C","author_residue_number":"39","distance_angstrom":3.5451,"insertion_code":null,"residue_name":"ASN"},"nearest_distance_angstrom":3.5451,"recommended_target_atom":"CG","residue_name":"GLU"},{"auth_chain_id":"B","author_residue_number":"220","contacting_atom_pair_count":15,"contacting_partner_residue_count":2,"insertion_code":null,"nearest_binder_contact":{"atom_name":"CB","auth_chain_id":"C","author_residue_number":"12","distance_angstrom":3.6586,"insertion_code":null,"residue_name":"ASP"},"nearest_distance_angstrom":3.6586,"recommended_target_atom":"O","residue_name":"ASP"},{"auth_chain_id":"B","author_residue_number":"217","contacting_atom_pair_count":8,"contacting_partner_residue_count":2,"insertion_code":null,"nearest_binder_contact":{"atom_name":"OD2","auth_chain_id":"C","author_residue_number":"12","distance_angstrom":3.6606,"insertion_code":null,"residue_name":"ASP"},"nearest_distance_angstrom":3.6606,"recommended_target_atom":"CA","residue_name":"ALA"}],"selection_rule":["descending count of distinct contacting binder residues","descending contacting heavy-atom pair count","ascending nearest heavy-atom distance","author chain and residue number for deterministic ties"],"use":"target-conditioned geometry-recovery control; review before a therapeutic design campaign"},"residue_contact_pairs":[{"binder":{"auth_chain_id":"C","author_residue_number":"65","insertion_code":null,"residue_name":"PRO"},"contacting_atom_pair_count":1,"nearest_binder_atom":"CB","nearest_distance_angstrom":4.4582,"nearest_target_atom":"OD2","target":{"auth_chain_id":"A","author_residue_number":"148","insertion_code":null,"residue_name":"ASP"}},{"binder":{"auth_chain_id":"C","author_residue_number":"66","insertion_code":null,"residue_name":"ARG"},"contacting_atom_pair_count":6,"nearest_binder_atom":"NH1","nearest_distance_angstrom":4.0527,"nearest_target_atom":"OD1","target":{"auth_chain_id":"A","author_residue_number":"148","insertion_code":null,"residue_name":"ASP"}},{"binder":{"auth_chain_id":"C","author_residue_number":"66","insertion_code":null,"residue_name":"ARG"},"contacting_atom_pair_count":4,"nearest_binder_atom":"NH2","nearest_distance_angstrom":4.4924,"nearest_target_atom":"CB","target":{"auth_chain_id":"A","author_residue_number":"149","insertion_code":null,"residue_name":"ALA"}},{"binder":{"auth_chain_id":"C","author_residue_number":"65","insertion_code":null,"residue_name":"PRO"},"contacting_atom_pair_count":6,"nearest_binder_atom":"O","nearest_distance_angstrom":3.9729,"nearest_target_atom":"OD2","target":{"auth_chain_id":"A","author_residue_number":"150","insertion_code":null,"residue_name":"ASP"}},{"binder":{"auth_chain_id":"C","author_residue_number":"66","insertion_code":null,"residue_name":"ARG"},"contacting_atom_pair_count":19,"nearest_binder_atom":"CA","nearest_distance_angstrom":3.418,"nearest_target_atom":"OD1","target":{"auth_chain_id":"A","author_residue_number":"150","insertion_code":null,"residue_name":"ASP"}},{"binder":{"auth_chain_id":"C","author_residue_number":"10","insertion_code":null,"residue_name":"ARG"},"contacting_atom_pair_count":1,"nearest_binder_atom":"NH1","nearest_distance_angstrom":4.6131,"nearest_target_atom":"O","target":{"auth_chain_id":"A","author_residue_number":"177","insertion_code":null,"residue_name":"PHE"}},{"binder":{"auth_chain_id":"C","author_residue_number":"10","insertion_code":null,"residue_name":"ARG"},"contacting_atom_pair_count":41,"nearest_binder_atom":"CD","nearest_distance_angstrom":3.5114,"nearest_target_atom":"CD2","target":{"auth_chain_id":"A","author_residue_number":"178","insertion_code":null,"residue_name":"TYR"}},{"binder":{"auth_chain_id":"C","author_residue_number":"11","insertion_code":null,"residue_name":"GLY"},"contacting_atom_pair_count":5,"nearest_binder_atom":"N","nearest_distance_angstrom":4.2199,"nearest_target_atom":"CE1","target":{"auth_chain_id":"A","author_residue_number":"178","insertion_code":null,"residue_name":"TYR"}},{"binder":{"auth_chain_id":"C","author_residue_number":"17","insertion_code":null,"residue_name":"MET"},"contacting_atom_pair_count":1,"nearest_binder_atom":"CE","nearest_distance_angstrom":4.8397,"nearest_target_atom":"OH","target":{"auth_chain_id":"A","author_residue_number":"178","insertion_code":null,"residue_name":"TYR"}},{"binder":{"auth_chain_id":"C","author_residue_number":"66","insertion_code":null,"residue_name":"ARG"},"contacting_atom_pair_count":15,"nearest_binder_atom":"CD","nearest_distance_angstrom":3.4168,"nearest_target_atom":"OH","target":{"auth_chain_id":"A","author_residue_number":"178","insertion_code":null,"residue_name":"TYR"}},{"binder":{"auth_chain_id":"C","author_residue_number":"10","insertion_code":null,"residue_name":"ARG"},"contacting_atom_pair_count":4,"nearest_binder_atom":"NH1","nearest_distance_angstrom":3.2176,"nearest_target_atom":"NE2","target":{"auth_chain_id":"A","author_residue_number":"180","insertion_code":null,"residue_name":"GLN"}},{"binder":{"auth_chain_id":"C","author_residue_number":"10","insertion_code":null,"residue_name":"ARG"},"contacting_atom_pair_count":1,"nearest_binder_atom":"NH1","nearest_distance_angstrom":4.4431,"nearest_target_atom":"OG1","target":{"auth_chain_id":"A","author_residue_number":"212","insertion_code":null,"residue_name":"THR"}},{"binder":{"auth_chain_id":"C","author_residue_number":"10","insertion_code":null,"residue_name":"ARG"},"contacting_atom_pair_count":5,"nearest_binder_atom":"NH2","nearest_distance_angstrom":3.1798,"nearest_target_atom":"O","target":{"auth_chain_id":"A","author_residue_number":"213","insertion_code":null,"residue_name":"ALA"}},{"binder":{"auth_chain_id":"C","author_residue_number":"10","insertion_code":null,"residue_name":"ARG"},"contacting_atom_pair_count":8,"nearest_binder_atom":"NH2","nearest_distance_angstrom":3.7178,"nearest_target_atom":"C","target":{"auth_chain_id":"A","author_residue_number":"214","insertion_code":null,"residue_name":"GLN"}},{"binder":{"auth_chain_id":"C","author_residue_number":"8","insertion_code":null,"residue_name":"VAL"},"contacting_atom_pair_count":1,"nearest_binder_atom":"CG1","nearest_distance_angstrom":4.3173,"nearest_target_atom":"CB","target":{"auth_chain_id":"A","author_residue_number":"215","insertion_code":null,"residue_name":"ALA"}},{"binder":{"auth_chain_id":"C","author_residue_number":"10","insertion_code":null,"residue_name":"ARG"},"contacting_atom_pair_count":15,"nearest_binder_atom":"NH2","nearest_distance_angstrom":3.3304,"nearest_target_atom":"N","target":{"auth_chain_id":"A","author_residue_number":"215","insertion_code":null,"residue_name":"ALA"}},{"binder":{"auth_chain_id":"C","author_residue_number":"10","insertion_code":null,"residue_name":"ARG"},"contacting_atom_pair_count":17,"nearest_binder_atom":"NH1","nearest_distance_angstrom":3.1597,"nearest_target_atom":"OD1","target":{"auth_chain_id":"A","author_residue_number":"218","insertion_code":null,"residue_name":"ASP"}},{"binder":{"auth_chain_id":"C","author_residue_number":"12","insertion_code":null,"residue_name":"ASP"},"contacting_atom_pair_count":14,"nearest_binder_atom":"OD1","nearest_distance_angstrom":2.8149,"nearest_target_atom":"OG","target":{"auth_chain_id":"B","author_residue_number":"125","insertion_code":null,"residue_name":"SER"}},{"binder":{"auth_chain_id":"C","author_residue_number":"12","insertion_code":null,"residue_name":"ASP"},"contacting_atom_pair_count":23,"nearest_binder_atom":"OD2","nearest_distance_angstrom":2.7561,"nearest_target_atom":"N","target":{"auth_chain_id":"B","author_residue_number":"126","insertion_code":null,"residue_name":"ALA"}},{"binder":{"auth_chain_id":"C","author_residue_number":"13","insertion_code":null,"residue_name":"LEU"},"contacting_atom_pair_count":5,"nearest_binder_atom":"CD2","nearest_distance_angstrom":3.7955,"nearest_target_atom":"CB","target":{"auth_chain_id":"B","author_residue_number":"126","insertion_code":null,"residue_name":"ALA"}},{"binder":{"auth_chain_id":"C","author_residue_number":"15","insertion_code":null,"residue_name":"GLU"},"contacting_atom_pair_count":3,"nearest_binder_atom":"CB","nearest_distance_angstrom":4.1165,"nearest_target_atom":"O","target":{"auth_chain_id":"B","author_residue_number":"126","insertion_code":null,"residue_name":"ALA"}},{"binder":{"auth_chain_id":"C","author_residue_number":"16","insertion_code":null,"residue_name":"LEU"},"contacting_atom_pair_count":8,"nearest_binder_atom":"CD1","nearest_distance_angstrom":3.7811,"nearest_target_atom":"CB","target":{"auth_chain_id":"B","author_residue_number":"126","insertion_code":null,"residue_name":"ALA"}},{"binder":{"auth_chain_id":"C","author_residue_number":"12","insertion_code":null,"residue_name":"ASP"},"contacting_atom_pair_count":22,"nearest_binder_atom":"OD1","nearest_distance_angstrom":2.9572,"nearest_target_atom":"N","target":{"auth_chain_id":"B","author_residue_number":"127","insertion_code":null,"residue_name":"SER"}},{"binder":{"auth_chain_id":"C","author_residue_number":"15","insertion_code":null,"residue_name":"GLU"},"contacting_atom_pair_count":11,"nearest_binder_atom":"CG","nearest_distance_angstrom":3.6099,"nearest_target_atom":"O","target":{"auth_chain_id":"B","author_residue_number":"127","insertion_code":null,"residue_name":"SER"}},{"binder":{"auth_chain_id":"C","author_residue_number":"15","insertion_code":null,"residue_name":"GLU"},"contacting_atom_pair_count":1,"nearest_binder_atom":"CB","nearest_distance_angstrom":4.763,"nearest_target_atom":"CB","target":{"auth_chain_id":"B","author_residue_number":"129","insertion_code":null,"residue_name":"ASP"}},{"binder":{"auth_chain_id":"C","author_residue_number":"16","insertion_code":null,"residue_name":"LEU"},"contacting_atom_pair_count":7,"nearest_binder_atom":"CD2","nearest_distance_angstrom":3.6837,"nearest_target_atom":"OD2","target":{"auth_chain_id":"B","author_residue_number":"129","insertion_code":null,"residue_name":"ASP"}},{"binder":{"auth_chain_id":"C","author_residue_number":"19","insertion_code":null,"residue_name":"ARG"},"contacting_atom_pair_count":9,"nearest_binder_atom":"NH1","nearest_distance_angstrom":2.9302,"nearest_target_atom":"OD2","target":{"auth_chain_id":"B","author_residue_number":"129","insertion_code":null,"residue_name":"ASP"}},{"binder":{"auth_chain_id":"C","author_residue_number":"15","insertion_code":null,"residue_name":"GLU"},"contacting_atom_pair_count":18,"nearest_binder_atom":"OE2","nearest_distance_angstrom":3.5484,"nearest_target_atom":"CG","target":{"auth_chain_id":"B","author_residue_number":"130","insertion_code":null,"residue_name":"ASP"}},{"binder":{"auth_chain_id":"C","author_residue_number":"66","insertion_code":null,"residue_name":"ARG"},"contacting_atom_pair_count":2,"nearest_binder_atom":"NH1","nearest_distance_angstrom":4.8287,"nearest_target_atom":"NZ","target":{"auth_chain_id":"B","author_residue_number":"170","insertion_code":null,"residue_name":"LYS"}},{"binder":{"auth_chain_id":"C","author_residue_number":"13","insertion_code":null,"residue_name":"LEU"},"contacting_atom_pair_count":4,"nearest_binder_atom":"CD2","nearest_distance_angstrom":4.1074,"nearest_target_atom":"O","target":{"auth_chain_id":"B","author_residue_number":"179","insertion_code":null,"residue_name":"PRO"}},{"binder":{"auth_chain_id":"C","author_residue_number":"13","insertion_code":null,"residue_name":"LEU"},"contacting_atom_pair_count":3,"nearest_binder_atom":"CD2","nearest_distance_angstrom":4.3919,"nearest_target_atom":"SG","target":{"auth_chain_id":"B","author_residue_number":"180","insertion_code":null,"residue_name":"CYS"}},{"binder":{"auth_chain_id":"C","author_residue_number":"16","insertion_code":null,"residue_name":"LEU"},"contacting_atom_pair_count":2,"nearest_binder_atom":"CD1","nearest_distance_angstrom":3.6506,"nearest_target_atom":"SG","target":{"auth_chain_id":"B","author_residue_number":"180","insertion_code":null,"residue_name":"CYS"}},{"binder":{"auth_chain_id":"C","author_residue_number":"63","insertion_code":null,"residue_name":"ARG"},"contacting_atom_pair_count":8,"nearest_binder_atom":"NH1","nearest_distance_angstrom":2.6631,"nearest_target_atom":"O","target":{"auth_chain_id":"B","author_residue_number":"182","insertion_code":null,"residue_name":"SER"}},{"binder":{"auth_chain_id":"C","author_residue_number":"13","insertion_code":null,"residue_name":"LEU"},"contacting_atom_pair_count":5,"nearest_binder_atom":"CD2","nearest_distance_angstrom":4.0573,"nearest_target_atom":"CD1","target":{"auth_chain_id":"B","author_residue_number":"183","insertion_code":null,"residue_name":"ILE"}},{"binder":{"auth_chain_id":"C","author_residue_number":"16","insertion_code":null,"residue_name":"LEU"},"contacting_atom_pair_count":7,"nearest_binder_atom":"CD1","nearest_distance_angstrom":3.6896,"nearest_target_atom":"CD1","target":{"auth_chain_id":"B","author_residue_number":"183","insertion_code":null,"residue_name":"ILE"}},{"binder":{"auth_chain_id":"C","author_residue_number":"17","insertion_code":null,"residue_name":"MET"},"contacting_atom_pair_count":2,"nearest_binder_atom":"CG","nearest_distance_angstrom":4.9477,"nearest_target_atom":"CG1","target":{"auth_chain_id":"B","author_residue_number":"183","insertion_code":null,"residue_name":"ILE"}},{"binder":{"auth_chain_id":"C","author_residue_number":"20","insertion_code":null,"residue_name":"ALA"},"contacting_atom_pair_count":2,"nearest_binder_atom":"CB","nearest_distance_angstrom":4.5343,"nearest_target_atom":"CG2","target":{"auth_chain_id":"B","author_residue_number":"183","insertion_code":null,"residue_name":"ILE"}},{"binder":{"auth_chain_id":"C","author_residue_number":"63","insertion_code":null,"residue_name":"ARG"},"contacting_atom_pair_count":14,"nearest_binder_atom":"NH1","nearest_distance_angstrom":2.6586,"nearest_target_atom":"O","target":{"auth_chain_id":"B","author_residue_number":"183","insertion_code":null,"residue_name":"ILE"}},{"binder":{"auth_chain_id":"C","author_residue_number":"64","insertion_code":null,"residue_name":"PHE"},"contacting_atom_pair_count":9,"nearest_binder_atom":"CE1","nearest_distance_angstrom":3.642,"nearest_target_atom":"O","target":{"auth_chain_id":"B","author_residue_number":"183","insertion_code":null,"residue_name":"ILE"}},{"binder":{"auth_chain_id":"C","author_residue_number":"63","insertion_code":null,"residue_name":"ARG"},"contacting_atom_pair_count":7,"nearest_binder_atom":"NH2","nearest_distance_angstrom":3.9697,"nearest_target_atom":"CD","target":{"auth_chain_id":"B","author_residue_number":"184","insertion_code":null,"residue_name":"PRO"}},{"binder":{"auth_chain_id":"C","author_residue_number":"16","insertion_code":null,"residue_name":"LEU"},"contacting_atom_pair_count":14,"nearest_binder_atom":"CD1","nearest_distance_angstrom":3.9558,"nearest_target_atom":"CD2","target":{"auth_chain_id":"B","author_residue_number":"185","insertion_code":null,"residue_name":"TYR"}},{"binder":{"auth_chain_id":"C","author_residue_number":"16","insertion_code":null,"residue_name":"LEU"},"contacting_atom_pair_count":1,"nearest_binder_atom":"CD1","nearest_distance_angstrom":4.9802,"nearest_target_atom":"CG2","target":{"auth_chain_id":"B","author_residue_number":"215","insertion_code":null,"residue_name":"ILE"}},{"binder":{"auth_chain_id":"C","author_residue_number":"12","insertion_code":null,"residue_name":"ASP"},"contacting_atom_pair_count":1,"nearest_binder_atom":"OD2","nearest_distance_angstrom":4.5539,"nearest_target_atom":"O","target":{"auth_chain_id":"B","author_residue_number":"216","insertion_code":null,"residue_name":"SER"}},{"binder":{"auth_chain_id":"C","author_residue_number":"12","insertion_code":null,"residue_name":"ASP"},"contacting_atom_pair_count":6,"nearest_binder_atom":"OD2","nearest_distance_angstrom":3.6606,"nearest_target_atom":"CA","target":{"auth_chain_id":"B","author_residue_number":"217","insertion_code":null,"residue_name":"ALA"}},{"binder":{"auth_chain_id":"C","author_residue_number":"13","insertion_code":null,"residue_name":"LEU"},"contacting_atom_pair_count":2,"nearest_binder_atom":"CD2","nearest_distance_angstrom":3.7952,"nearest_target_atom":"CB","target":{"auth_chain_id":"B","author_residue_number":"217","insertion_code":null,"residue_name":"ALA"}},{"binder":{"auth_chain_id":"C","author_residue_number":"12","insertion_code":null,"residue_name":"ASP"},"contacting_atom_pair_count":31,"nearest_binder_atom":"OD2","nearest_distance_angstrom":3.1197,"nearest_target_atom":"N","target":{"auth_chain_id":"B","author_residue_number":"218","insertion_code":null,"residue_name":"ASN"}},{"binder":{"auth_chain_id":"C","author_residue_number":"13","insertion_code":null,"residue_name":"LEU"},"contacting_atom_pair_count":5,"nearest_binder_atom":"CG","nearest_distance_angstrom":3.8841,"nearest_target_atom":"O","target":{"auth_chain_id":"B","author_residue_number":"218","insertion_code":null,"residue_name":"ASN"}},{"binder":{"auth_chain_id":"C","author_residue_number":"11","insertion_code":null,"residue_name":"GLY"},"contacting_atom_pair_count":6,"nearest_binder_atom":"CA","nearest_distance_angstrom":3.3459,"nearest_target_atom":"O","target":{"auth_chain_id":"B","author_residue_number":"219","insertion_code":null,"residue_name":"ILE"}},{"binder":{"auth_chain_id":"C","author_residue_number":"12","insertion_code":null,"residue_name":"ASP"},"contacting_atom_pair_count":10,"nearest_binder_atom":"N","nearest_distance_angstrom":2.9783,"nearest_target_atom":"O","target":{"auth_chain_id":"B","author_residue_number":"219","insertion_code":null,"residue_name":"ILE"}},{"binder":{"auth_chain_id":"C","author_residue_number":"13","insertion_code":null,"residue_name":"LEU"},"contacting_atom_pair_count":1,"nearest_binder_atom":"N","nearest_distance_angstrom":4.705,"nearest_target_atom":"O","target":{"auth_chain_id":"B","author_residue_number":"219","insertion_code":null,"residue_name":"ILE"}},{"binder":{"auth_chain_id":"C","author_residue_number":"66","insertion_code":null,"residue_name":"ARG"},"contacting_atom_pair_count":1,"nearest_binder_atom":"NH2","nearest_distance_angstrom":4.5153,"nearest_target_atom":"CG2","target":{"auth_chain_id":"B","author_residue_number":"219","insertion_code":null,"residue_name":"ILE"}},{"binder":{"auth_chain_id":"C","author_residue_number":"11","insertion_code":null,"residue_name":"GLY"},"contacting_atom_pair_count":4,"nearest_binder_atom":"CA","nearest_distance_angstrom":4.4846,"nearest_target_atom":"C","target":{"auth_chain_id":"B","author_residue_number":"220","insertion_code":null,"residue_name":"ASP"}},{"binder":{"auth_chain_id":"C","author_residue_number":"12","insertion_code":null,"residue_name":"ASP"},"contacting_atom_pair_count":11,"nearest_binder_atom":"CB","nearest_distance_angstrom":3.6586,"nearest_target_atom":"O","target":{"auth_chain_id":"B","author_residue_number":"220","insertion_code":null,"residue_name":"ASP"}},{"binder":{"auth_chain_id":"C","author_residue_number":"10","insertion_code":null,"residue_name":"ARG"},"contacting_atom_pair_count":1,"nearest_binder_atom":"C","nearest_distance_angstrom":4.9855,"nearest_target_atom":"OG1","target":{"auth_chain_id":"B","author_residue_number":"221","insertion_code":null,"residue_name":"THR"}},{"binder":{"auth_chain_id":"C","author_residue_number":"11","insertion_code":null,"residue_name":"GLY"},"contacting_atom_pair_count":10,"nearest_binder_atom":"CA","nearest_distance_angstrom":3.6279,"nearest_target_atom":"OG1","target":{"auth_chain_id":"B","author_residue_number":"221","insertion_code":null,"residue_name":"THR"}},{"binder":{"auth_chain_id":"C","author_residue_number":"12","insertion_code":null,"residue_name":"ASP"},"contacting_atom_pair_count":5,"nearest_binder_atom":"N","nearest_distance_angstrom":4.1853,"nearest_target_atom":"N","target":{"auth_chain_id":"B","author_residue_number":"221","insertion_code":null,"residue_name":"THR"}},{"binder":{"auth_chain_id":"C","author_residue_number":"12","insertion_code":null,"residue_name":"ASP"},"contacting_atom_pair_count":10,"nearest_binder_atom":"OD1","nearest_distance_angstrom":2.9806,"nearest_target_atom":"OE2","target":{"auth_chain_id":"B","author_residue_number":"223","insertion_code":null,"residue_name":"GLU"}},{"binder":{"auth_chain_id":"C","author_residue_number":"39","insertion_code":null,"residue_name":"ASN"},"contacting_atom_pair_count":3,"nearest_binder_atom":"ND2","nearest_distance_angstrom":4.2451,"nearest_target_atom":"OE1","target":{"auth_chain_id":"B","author_residue_number":"315","insertion_code":null,"residue_name":"GLN"}},{"binder":{"auth_chain_id":"C","author_residue_number":"39","insertion_code":null,"residue_name":"ASN"},"contacting_atom_pair_count":13,"nearest_binder_atom":"OD1","nearest_distance_angstrom":3.5451,"nearest_target_atom":"CG","target":{"auth_chain_id":"B","author_residue_number":"316","insertion_code":null,"residue_name":"GLU"}},{"binder":{"auth_chain_id":"C","author_residue_number":"41","insertion_code":null,"residue_name":"LYS"},"contacting_atom_pair_count":7,"nearest_binder_atom":"NZ","nearest_distance_angstrom":3.6061,"nearest_target_atom":"OE2","target":{"auth_chain_id":"B","author_residue_number":"316","insertion_code":null,"residue_name":"GLU"}}],"schema_version":"surface-atlas-reference-interface/v1","selection":{"alternate_location_policy":"blank-or-A","binder_auth_chain_ids":["C"],"contact_threshold_angstrom":5.0,"deposited_model_number":1,"distance_definition":"minimum Euclidean distance between retained heavy-atom coordinates","heavy_atoms_only":true,"polymer_residues_only":true,"target_auth_chain_ids":["A","B"],"threshold_operator":"less-than-or-equal"},"source_coordinate":{"accession":"8TCG","bytes":1231593,"database":"RCSB Protein Data Bank","format":"mmcif","revision":"2024-11-06","sha256":"37ac1f450bbb1ced20744182635750a1e5e42733de2f25ae865362908d61e91d"},"target_interface_residues":[{"auth_chain_id":"A","author_residue_number":"148","contacting_atom_pair_count":7,"contacting_partner_residue_count":2,"insertion_code":null,"nearest_distance_angstrom":4.0527,"residue_name":"ASP"},{"auth_chain_id":"A","author_residue_number":"149","contacting_atom_pair_count":4,"contacting_partner_residue_count":1,"insertion_code":null,"nearest_distance_angstrom":4.4924,"residue_name":"ALA"},{"auth_chain_id":"A","author_residue_number":"150","contacting_atom_pair_count":25,"contacting_partner_residue_count":2,"insertion_code":null,"nearest_distance_angstrom":3.418,"residue_name":"ASP"},{"auth_chain_id":"A","author_residue_number":"177","contacting_atom_pair_count":1,"contacting_partner_residue_count":1,"insertion_code":null,"nearest_distance_angstrom":4.6131,"residue_name":"PHE"},{"auth_chain_id":"A","author_residue_number":"178","contacting_atom_pair_count":62,"contacting_partner_residue_count":4,"insertion_code":null,"nearest_distance_angstrom":3.4168,"residue_name":"TYR"},{"auth_chain_id":"A","author_residue_number":"180","contacting_atom_pair_count":4,"contacting_partner_residue_count":1,"insertion_code":null,"nearest_distance_angstrom":3.2176,"residue_name":"GLN"},{"auth_chain_id":"A","author_residue_number":"212","contacting_atom_pair_count":1,"contacting_partner_residue_count":1,"insertion_code":null,"nearest_distance_angstrom":4.4431,"residue_name":"THR"},{"auth_chain_id":"A","author_residue_number":"213","contacting_atom_pair_count":5,"contacting_partner_residue_count":1,"insertion_code":null,"nearest_distance_angstrom":3.1798,"residue_name":"ALA"},{"auth_chain_id":"A","author_residue_number":"214","contacting_atom_pair_count":8,"contacting_partner_residue_count":1,"insertion_code":null,"nearest_distance_angstrom":3.7178,"residue_name":"GLN"},{"auth_chain_id":"A","author_residue_number":"215","contacting_atom_pair_count":16,"contacting_partner_residue_count":2,"insertion_code":null,"nearest_distance_angstrom":3.3304,"residue_name":"ALA"},{"auth_chain_id":"A","author_residue_number":"218","contacting_atom_pair_count":17,"contacting_partner_residue_count":1,"insertion_code":null,"nearest_distance_angstrom":3.1597,"residue_name":"ASP"},{"auth_chain_id":"B","author_residue_number":"125","contacting_atom_pair_count":14,"contacting_partner_residue_count":1,"insertion_code":null,"nearest_distance_angstrom":2.8149,"residue_name":"SER"},{"auth_chain_id":"B","author_residue_number":"126","contacting_atom_pair_count":39,"contacting_partner_residue_count":4,"insertion_code":null,"nearest_distance_angstrom":2.7561,"residue_name":"ALA"},{"auth_chain_id":"B","author_residue_number":"127","contacting_atom_pair_count":33,"contacting_partner_residue_count":2,"insertion_code":null,"nearest_distance_angstrom":2.9572,"residue_name":"SER"},{"auth_chain_id":"B","author_residue_number":"129","contacting_atom_pair_count":17,"contacting_partner_residue_count":3,"insertion_code":null,"nearest_distance_angstrom":2.9302,"residue_name":"ASP"},{"auth_chain_id":"B","author_residue_number":"130","contacting_atom_pair_count":18,"contacting_partner_residue_count":1,"insertion_code":null,"nearest_distance_angstrom":3.5484,"residue_name":"ASP"},{"auth_chain_id":"B","author_residue_number":"170","contacting_atom_pair_count":2,"contacting_partner_residue_count":1,"insertion_code":null,"nearest_distance_angstrom":4.8287,"residue_name":"LYS"},{"auth_chain_id":"B","author_residue_number":"179","contacting_atom_pair_count":4,"contacting_partner_residue_count":1,"insertion_code":null,"nearest_distance_angstrom":4.1074,"residue_name":"PRO"},{"auth_chain_id":"B","author_residue_number":"180","contacting_atom_pair_count":5,"contacting_partner_residue_count":2,"insertion_code":null,"nearest_distance_angstrom":3.6506,"residue_name":"CYS"},{"auth_chain_id":"B","author_residue_number":"182","contacting_atom_pair_count":8,"contacting_partner_residue_count":1,"insertion_code":null,"nearest_distance_angstrom":2.6631,"residue_name":"SER"},{"auth_chain_id":"B","author_residue_number":"183","contacting_atom_pair_count":39,"contacting_partner_residue_count":6,"insertion_code":null,"nearest_distance_angstrom":2.6586,"residue_name":"ILE"},{"auth_chain_id":"B","author_residue_number":"184","contacting_atom_pair_count":7,"contacting_partner_residue_count":1,"insertion_code":null,"nearest_distance_angstrom":3.9697,"residue_name":"PRO"},{"auth_chain_id":"B","author_residue_number":"185","contacting_atom_pair_count":14,"contacting_partner_residue_count":1,"insertion_code":null,"nearest_distance_angstrom":3.9558,"residue_name":"TYR"},{"auth_chain_id":"B","author_residue_number":"215","contacting_atom_pair_count":1,"contacting_partner_residue_count":1,"insertion_code":null,"nearest_distance_angstrom":4.9802,"residue_name":"ILE"},{"auth_chain_id":"B","author_residue_number":"216","contacting_atom_pair_count":1,"contacting_partner_residue_count":1,"insertion_code":null,"nearest_distance_angstrom":4.5539,"residue_name":"SER"},{"auth_chain_id":"B","author_residue_number":"217","contacting_atom_pair_count":8,"contacting_partner_residue_count":2,"insertion_code":null,"nearest_distance_angstrom":3.6606,"residue_name":"ALA"},{"auth_chain_id":"B","author_residue_number":"218","contacting_atom_pair_count":36,"contacting_partner_residue_count":2,"insertion_code":null,"nearest_distance_angstrom":3.1197,"residue_name":"ASN"},{"auth_chain_id":"B","author_residue_number":"219","contacting_atom_pair_count":18,"contacting_partner_residue_count":4,"insertion_code":null,"nearest_distance_angstrom":2.9783,"residue_name":"ILE"},{"auth_chain_id":"B","author_residue_number":"220","contacting_atom_pair_count":15,"contacting_partner_residue_count":2,"insertion_code":null,"nearest_distance_angstrom":3.6586,"residue_name":"ASP"},{"auth_chain_id":"B","author_residue_number":"221","contacting_atom_pair_count":16,"contacting_partner_residue_count":3,"insertion_code":null,"nearest_distance_angstrom":3.6279,"residue_name":"THR"},{"auth_chain_id":"B","author_residue_number":"223","contacting_atom_pair_count":10,"contacting_partner_residue_count":1,"insertion_code":null,"nearest_distance_angstrom":2.9806,"residue_name":"GLU"},{"auth_chain_id":"B","author_residue_number":"315","contacting_atom_pair_count":3,"contacting_partner_residue_count":1,"insertion_code":null,"nearest_distance_angstrom":4.2451,"residue_name":"GLN"},{"auth_chain_id":"B","author_residue_number":"316","contacting_atom_pair_count":20,"contacting_partner_residue_count":2,"insertion_code":null,"nearest_distance_angstrom":3.5451,"residue_name":"GLU"}]}