{"schema_version":"surface-report-candidate-files/v1","records":[{"campaign_id":"ceacam5-8bw0-multigenerator","arm_id":"boltzgen","stage":"smoke","source_candidate_id":"boltzgen-000","recovery_key":"ceacam5-8bw0-multigenerator/boltzgen/smoke/boltzgen-000","sequence":"MTWKVTFSDGRTGTTEGKPEVGKVLTVTYDDGSVSKVEVVEVVDDNTALVRNLETGEEADATAV","sequence_length":64,"sequence_sha256":"28152b2f7418717c770fce2bb3522edb44b1e0b4b1aaafeb5e22cf802452ac57","source_manifest_sha256":"25f7d4ffc507df18384e92a53554ae5d654348355740e2d9f3b5ecd7b412b5f5","sequence_artifact":{"path":"data/artifacts/binder-candidate-files/1772b39f705988e5f569-835b9c88ad53.fasta","sha256":"835b9c88ad53420ad91d985271eabe10a835d0969b808e5c2700c8759088d97c","bytes":79},"design_pose_artifact":{"path":"data/artifacts/binder-candidate-files/1772b39f705988e5f569-34c405561f55.pdb","sha256":"34c405561f55e41909a0f13fb04fa9abd6c5f0a25df7fa64281bf735bcf9da3e","bytes":149769,"original_source_sha256":"34c405561f55e41909a0f13fb04fa9abd6c5f0a25df7fa64281bf735bcf9da3e","coordinate_records_sha256":"ac9fbfc54fb04061c9a09393fb0c65115bb2628dc7e4c534452bf48b07b2925a"},"binder_chain_id":"B","observed_protein_chain_lengths":{"A":177,"B":64},"representation":"generated design pose","snapshot":{"path":"data/artifacts/binder-candidate-files/ca22954097091c351d38c37e.png","sha256":"ca22954097091c351d38c37ed4f48806256f62d2f594238fb3abc125c0b34329","title":"CEACAM5 · BoltzGen 000 · smoke","caption":"Generated design pose. CEACAM5 target (chain A); binder boltzgen-000 (chain B). Source status: generated. Screening state: not run; four-arm join incomplete. Ranking: unranked.","metadata_href":"data/artifacts/binder-candidate-files/ca22954097091c351d38c37e.snapshot.json","metadata_sha256":"92775482b3502ec27ca68b1ffa7a1665429fa9f58acbf774c7a124d94e12e3fd","width":960,"height":720,"coordinate_sources":[{"sha256":"34c405561f55e41909a0f13fb04fa9abd6c5f0a25df7fa64281bf735bcf9da3e","bytes":149769,"role":"generated-design-pose","object_name":"complex","state":1,"chain_namespace":"author","source_type":"polymer","expected_chains":["A","B"],"original_source_sha256":"34c405561f55e41909a0f13fb04fa9abd6c5f0a25df7fa64281bf735bcf9da3e","packaged_sha256":"34c405561f55e41909a0f13fb04fa9abd6c5f0a25df7fa64281bf735bcf9da3e","packaged_bytes":149769,"coordinate_href":"data/artifacts/binder-candidate-files/34c405561f55e41909a0f13f.pdb","removed_contact_metadata_fields":0,"format":"pdb"}],"layers":[{"color":"#17675D","color_mode":"solid","description":"Target chain A; source target geometry present.","name":"target","object_name":"complex","representation":"cartoon","selection":"polymer.protein and chain A","transparency":0.0},{"color":"#526A92","color_mode":"solid","description":"Generated binder chain B.","name":"binder","object_name":"complex","representation":"cartoon","selection":"polymer.protein and chain B","transparency":0.0}],"coordinate_kind":"generated","target_id":"ceacam5-8bw0-a3b3"}},{"campaign_id":"ceacam5-8bw0-multigenerator","arm_id":"boltzgen","stage":"scale","source_candidate_id":"boltzgen-000","recovery_key":"ceacam5-8bw0-multigenerator/boltzgen/scale/boltzgen-000","sequence":"GTAYATANLTKEEDVVGDIKATVVGTLPGGVKIVKATNLKSGAEVLHDVPGSKETATLAVPSSS","sequence_length":64,"sequence_sha256":"f3e48bd663bfecfb774556bbd3c8537fba17265d4869eaaf422fda1eb3b99455","source_manifest_sha256":"ce59cdb6e4c27c71b0a453a23733d874adef5f845376405878d2cd3f631f7af4","sequence_artifact":{"path":"data/artifacts/binder-candidate-files/f17b710e652fa22ada07-0583ff33c146.fasta","sha256":"0583ff33c14664c2fb6ad337f66187ad773ec95834820cd96c994a2f6d707cab","bytes":79},"design_pose_artifact":{"path":"data/artifacts/binder-candidate-files/f17b710e652fa22ada07-e61bd7d95f6c.pdb","sha256":"e61bd7d95f6c3f5e63bd0287696176fd6e146860f9624a93ee2ffbdc32ef7b9b","bytes":147258,"original_source_sha256":"e61bd7d95f6c3f5e63bd0287696176fd6e146860f9624a93ee2ffbdc32ef7b9b","coordinate_records_sha256":"cb7c07ddff23a8fb8a50a7a2a40ad6b874b6b7b06534b78b281f6436e92a85f5"},"binder_chain_id":"B","observed_protein_chain_lengths":{"A":177,"B":64},"representation":"generated design pose","snapshot":{"path":"data/artifacts/binder-candidate-files/3b1c63564c9cde2b52c5aaf9.png","sha256":"3b1c63564c9cde2b52c5aaf9372096c71816d233cc30bb27e15696f558e6e55a","title":"CEACAM5 · BoltzGen 000 · scale","caption":"Generated design pose. CEACAM5 target (chain A); binder boltzgen-000 (chain B). Source status: generated. Screening state: not run; four-arm join incomplete. Ranking: unranked.","metadata_href":"data/artifacts/binder-candidate-files/3b1c63564c9cde2b52c5aaf9.snapshot.json","metadata_sha256":"ceef17aef4efaacc7e5a8cf59d7815f2af646ab4ab04c225fffc7346b427218d","width":960,"height":720,"coordinate_sources":[{"sha256":"e61bd7d95f6c3f5e63bd0287696176fd6e146860f9624a93ee2ffbdc32ef7b9b","bytes":147258,"role":"generated-design-pose","object_name":"complex","state":1,"chain_namespace":"author","source_type":"polymer","expected_chains":["A","B"],"original_source_sha256":"e61bd7d95f6c3f5e63bd0287696176fd6e146860f9624a93ee2ffbdc32ef7b9b","packaged_sha256":"e61bd7d95f6c3f5e63bd0287696176fd6e146860f9624a93ee2ffbdc32ef7b9b","packaged_bytes":147258,"coordinate_href":"data/artifacts/binder-candidate-files/e61bd7d95f6c3f5e63bd0287.pdb","removed_contact_metadata_fields":0,"format":"pdb"}],"layers":[{"color":"#17675D","color_mode":"solid","description":"Target chain A; source target geometry present.","name":"target","object_name":"complex","representation":"cartoon","selection":"polymer.protein and chain A","transparency":0.0},{"color":"#526A92","color_mode":"solid","description":"Generated binder chain B.","name":"binder","object_name":"complex","representation":"cartoon","selection":"polymer.protein and chain B","transparency":0.0}],"coordinate_kind":"generated","target_id":"ceacam5-8bw0-a3b3"}},{"campaign_id":"ceacam5-8bw0-multigenerator","arm_id":"boltzgen","stage":"scale","source_candidate_id":"boltzgen-001","recovery_key":"ceacam5-8bw0-multigenerator/boltzgen/scale/boltzgen-001","sequence":"MEVTVTITKTSYLTDENIKSIIRSALLKAGVSEEEAEKLAEEALAKIKAAKPKVGETVTVTLKV","sequence_length":64,"sequence_sha256":"ccc912f3587e2527d082c7e39b439feda882f3a71a006545ee7561754977fcd2","source_manifest_sha256":"ce59cdb6e4c27c71b0a453a23733d874adef5f845376405878d2cd3f631f7af4","sequence_artifact":{"path":"data/artifacts/binder-candidate-files/5f1e948c3afc5bc6ac57-41f5bd6bd2a9.fasta","sha256":"41f5bd6bd2a9d149f86f5ea6e9d0f6ae6abe4070610d5148d9ca7f945c919468","bytes":79},"design_pose_artifact":{"path":"data/artifacts/binder-candidate-files/5f1e948c3afc5bc6ac57-2c2ce0876e14.pdb","sha256":"2c2ce0876e1495fa8014ff72e2d33071b1379585d9af004d9d4ae5d4326fb07f","bytes":150093,"original_source_sha256":"2c2ce0876e1495fa8014ff72e2d33071b1379585d9af004d9d4ae5d4326fb07f","coordinate_records_sha256":"7beebbc81a6883915f63d32705cc28765d3d8436178a8185e91682ddfc468836"},"binder_chain_id":"B","observed_protein_chain_lengths":{"A":177,"B":64},"representation":"generated design pose","snapshot":{"path":"data/artifacts/binder-candidate-files/9d9d03fff37e00334949eb30.png","sha256":"9d9d03fff37e00334949eb30f431417a2004323fddbef2adaa95faeb3687d4b6","title":"CEACAM5 · BoltzGen 001 · scale","caption":"Generated design pose from the original four-arm campaign. This candidate was later screened in the three-arm checkpoint; the checkpoint failed its control check and no candidate was promoted.","metadata_href":"data/artifacts/binder-candidate-files/9d9d03fff37e00334949eb30.snapshot.json","metadata_sha256":"ac7b6ff685ac43334376515bf874569470a9d1459ca757fd3222f5287439a362","width":960,"height":720,"coordinate_sources":[{"sha256":"2c2ce0876e1495fa8014ff72e2d33071b1379585d9af004d9d4ae5d4326fb07f","bytes":150093,"role":"generated-design-pose","object_name":"complex","state":1,"chain_namespace":"author","source_type":"polymer","expected_chains":["A","B"],"original_source_sha256":"2c2ce0876e1495fa8014ff72e2d33071b1379585d9af004d9d4ae5d4326fb07f","packaged_sha256":"2c2ce0876e1495fa8014ff72e2d33071b1379585d9af004d9d4ae5d4326fb07f","packaged_bytes":150093,"coordinate_href":"data/artifacts/binder-candidate-files/2c2ce0876e1495fa8014ff72.pdb","removed_contact_metadata_fields":0,"format":"pdb"}],"layers":[{"color":"#17675D","color_mode":"solid","description":"Target chain A; source target geometry present.","name":"target","object_name":"complex","representation":"cartoon","selection":"polymer.protein and chain A","transparency":0.0},{"color":"#526A92","color_mode":"solid","description":"Generated binder chain B.","name":"binder","object_name":"complex","representation":"cartoon","selection":"polymer.protein and chain B","transparency":0.0}],"coordinate_kind":"generated","target_id":"ceacam5-8bw0-a3b3"}},{"campaign_id":"ceacam5-8bw0-multigenerator","arm_id":"proteina-complexa","stage":"smoke","source_candidate_id":"proteina-complexa-000","recovery_key":"ceacam5-8bw0-multigenerator/proteina-complexa/smoke/proteina-complexa-000","sequence":"QAFREFDKDGNGYISTKELGTVMRSLGQNPTEAELQDMINEQDADGDGTISFEEFSTMMRSLGM","sequence_length":64,"sequence_sha256":"f3fcb1023fa52085b79f633d631390733c868ee809fa84a0765cc5718691e443","source_manifest_sha256":"e8b3451955d98b9ac7f8f659acf3bea931b8874b7db5fa6cb029e9384e83e15c","sequence_artifact":{"path":"data/artifacts/binder-candidate-files/ce62b08cfae7cfe57201-301a09177e3e.fasta","sha256":"301a09177e3e52bb8f589d407ab06c08f6e210e1c9fce8e8b9bdcd8fa57d3f3e","bytes":96},"design_pose_artifact":{"path":"data/artifacts/binder-candidate-files/ce62b08cfae7cfe57201-a7b368ee080d.pdb","sha256":"a7b368ee080db8d30c21df05180ce704cbe2585f88f8071641b9742852e4ff99","bytes":149691,"original_source_sha256":"a7b368ee080db8d30c21df05180ce704cbe2585f88f8071641b9742852e4ff99","coordinate_records_sha256":"182222ff626f1f549fdd3ab6661752c54e2df042e0c01745cc1653729323937b"},"binder_chain_id":"B","observed_protein_chain_lengths":{"A":177,"B":64},"representation":"generated design pose","snapshot":{"path":"data/artifacts/binder-candidate-files/32e65e30e25f86b5b1aa2015.png","sha256":"32e65e30e25f86b5b1aa20153f1de554d2919e62ce6c6589145027756d807cbd","title":"CEACAM5 · Proteina Complexa 000 · smoke","caption":"Generated design pose. CEACAM5 target (chain A); binder proteina-complexa-000 (chain B). Source status: generated. Screening state: not run; four-arm join incomplete. Ranking: unranked.","metadata_href":"data/artifacts/binder-candidate-files/32e65e30e25f86b5b1aa2015.snapshot.json","metadata_sha256":"3a2cb37804ee55ac8c440e116dfc11921ee915f9336795afc9650fb729f962c4","width":960,"height":720,"coordinate_sources":[{"sha256":"a7b368ee080db8d30c21df05180ce704cbe2585f88f8071641b9742852e4ff99","bytes":149691,"role":"generated-design-pose","object_name":"complex","state":1,"chain_namespace":"author","source_type":"polymer","expected_chains":["A","B"],"original_source_sha256":"a7b368ee080db8d30c21df05180ce704cbe2585f88f8071641b9742852e4ff99","packaged_sha256":"a7b368ee080db8d30c21df05180ce704cbe2585f88f8071641b9742852e4ff99","packaged_bytes":149691,"coordinate_href":"data/artifacts/binder-candidate-files/a7b368ee080db8d30c21df05.pdb","removed_contact_metadata_fields":0,"format":"pdb"}],"layers":[{"color":"#17675D","color_mode":"solid","description":"Target chain A; source target geometry present.","name":"target","object_name":"complex","representation":"cartoon","selection":"polymer.protein and chain A","transparency":0.0},{"color":"#526A92","color_mode":"solid","description":"Generated binder chain B.","name":"binder","object_name":"complex","representation":"cartoon","selection":"polymer.protein and chain B","transparency":0.0}],"coordinate_kind":"generated","target_id":"ceacam5-8bw0-a3b3"}},{"campaign_id":"ceacam5-8bw0-multigenerator","arm_id":"proteina-complexa","stage":"scale","source_candidate_id":"proteina-complexa-000","recovery_key":"ceacam5-8bw0-multigenerator/proteina-complexa/scale/proteina-complexa-000","sequence":"SKLKQLRVEHLERTLLEGVLENGQVTFPTLTAEDYELLRTLPRDKQELLAQRFNVSVESFCPAA","sequence_length":64,"sequence_sha256":"238c73b712b8664a3722299b5ed7cc094548c5723ff37792d7e5b5d1d0c42414","source_manifest_sha256":"7b1a74b161ad50d73e83e09fc919f49c97d417349c6d174825f67f261e1a38fa","sequence_artifact":{"path":"data/artifacts/binder-candidate-files/549a0ad1fdcf21bf6e3a-90eb5f9dff49.fasta","sha256":"90eb5f9dff49f2fab8a81028791cdc5cde77de39db9992501aba10557b1ebc3e","bytes":96},"design_pose_artifact":{"path":"data/artifacts/binder-candidate-files/549a0ad1fdcf21bf6e3a-cd6f93802c46.pdb","sha256":"cd6f93802c466ab7e0c2f79f58c1563e3938edf92b661770d5de9e10d5974a4d","bytes":151311,"original_source_sha256":"cd6f93802c466ab7e0c2f79f58c1563e3938edf92b661770d5de9e10d5974a4d","coordinate_records_sha256":"dc9022873224a9ebb6d75b252fcf0d214a0736885bf2285ea53109d61c493c53"},"binder_chain_id":"B","observed_protein_chain_lengths":{"A":177,"B":64},"representation":"generated design pose","snapshot":{"path":"data/artifacts/binder-candidate-files/0e08936b20e07ed86e24ed0a.png","sha256":"0e08936b20e07ed86e24ed0a97dbea0b0749cdf6bb0ea3801ecf6b2135bd9756","title":"CEACAM5 · Proteina Complexa 000 · scale","caption":"Generated design pose from the original four-arm campaign. This candidate was later screened in the three-arm checkpoint; the checkpoint failed its control check and no candidate was promoted.","metadata_href":"data/artifacts/binder-candidate-files/0e08936b20e07ed86e24ed0a.snapshot.json","metadata_sha256":"5ff810fce16c47f04114e72836c70b25936acc348fffc2350b6713a008fdad3d","width":960,"height":720,"coordinate_sources":[{"sha256":"cd6f93802c466ab7e0c2f79f58c1563e3938edf92b661770d5de9e10d5974a4d","bytes":151311,"role":"generated-design-pose","object_name":"complex","state":1,"chain_namespace":"author","source_type":"polymer","expected_chains":["A","B"],"original_source_sha256":"cd6f93802c466ab7e0c2f79f58c1563e3938edf92b661770d5de9e10d5974a4d","packaged_sha256":"cd6f93802c466ab7e0c2f79f58c1563e3938edf92b661770d5de9e10d5974a4d","packaged_bytes":151311,"coordinate_href":"data/artifacts/binder-candidate-files/cd6f93802c466ab7e0c2f79f.pdb","removed_contact_metadata_fields":0,"format":"pdb"}],"layers":[{"color":"#17675D","color_mode":"solid","description":"Target chain A; source target geometry present.","name":"target","object_name":"complex","representation":"cartoon","selection":"polymer.protein and chain A","transparency":0.0},{"color":"#526A92","color_mode":"solid","description":"Generated binder chain B.","name":"binder","object_name":"complex","representation":"cartoon","selection":"polymer.protein and chain B","transparency":0.0}],"coordinate_kind":"generated","target_id":"ceacam5-8bw0-a3b3"}},{"campaign_id":"ceacam5-8bw0-multigenerator","arm_id":"proteina-complexa","stage":"scale","source_candidate_id":"proteina-complexa-001","recovery_key":"ceacam5-8bw0-multigenerator/proteina-complexa/scale/proteina-complexa-001","sequence":"NIYLNLALLYEKLGNKEGAAEAYLQAAQIFYQLGNTDLAIKAAEQANKIYEELGDTSKILNLTS","sequence_length":64,"sequence_sha256":"493fcdfa980f4f969d0729a1fc59983ebfc076b1b3100ef4610e6383034dcff0","source_manifest_sha256":"7b1a74b161ad50d73e83e09fc919f49c97d417349c6d174825f67f261e1a38fa","sequence_artifact":{"path":"data/artifacts/binder-candidate-files/9cfcddc245d4f527c7ff-c65b7ddce029.fasta","sha256":"c65b7ddce029f6b3dca2195c0e81c301c6364e8d70682fb0182ad0882e70baf8","bytes":96},"design_pose_artifact":{"path":"data/artifacts/binder-candidate-files/9cfcddc245d4f527c7ff-6fe046449c14.pdb","sha256":"6fe046449c149dab304990ea2e7bd7074e076ffc4552e78a13c178b7423516d1","bytes":149772,"original_source_sha256":"6fe046449c149dab304990ea2e7bd7074e076ffc4552e78a13c178b7423516d1","coordinate_records_sha256":"d7f6eff2986f036f46f103dc3dd024df4f180abe9c8ca3ab6db606c17ddaa59b"},"binder_chain_id":"B","observed_protein_chain_lengths":{"A":177,"B":64},"representation":"generated design pose","snapshot":{"path":"data/artifacts/binder-candidate-files/d6eaf88ee958003d9591b809.png","sha256":"d6eaf88ee958003d9591b809ec1afab0c3e9f0723681934d87c6ae69f393f127","title":"CEACAM5 · Proteina Complexa 001 · scale","caption":"Generated design pose from the original four-arm campaign. This candidate was later screened in the three-arm checkpoint; the checkpoint failed its control check and no candidate was promoted.","metadata_href":"data/artifacts/binder-candidate-files/d6eaf88ee958003d9591b809.snapshot.json","metadata_sha256":"977a99507e421b6ddbe7ffea4fb41c70b748dd268156df0f2cdbf72edf624db1","width":960,"height":720,"coordinate_sources":[{"sha256":"6fe046449c149dab304990ea2e7bd7074e076ffc4552e78a13c178b7423516d1","bytes":149772,"role":"generated-design-pose","object_name":"complex","state":1,"chain_namespace":"author","source_type":"polymer","expected_chains":["A","B"],"original_source_sha256":"6fe046449c149dab304990ea2e7bd7074e076ffc4552e78a13c178b7423516d1","packaged_sha256":"6fe046449c149dab304990ea2e7bd7074e076ffc4552e78a13c178b7423516d1","packaged_bytes":149772,"coordinate_href":"data/artifacts/binder-candidate-files/6fe046449c149dab304990ea.pdb","removed_contact_metadata_fields":0,"format":"pdb"}],"layers":[{"color":"#17675D","color_mode":"solid","description":"Target chain A; source target geometry present.","name":"target","object_name":"complex","representation":"cartoon","selection":"polymer.protein and chain A","transparency":0.0},{"color":"#526A92","color_mode":"solid","description":"Generated binder chain B.","name":"binder","object_name":"complex","representation":"cartoon","selection":"polymer.protein and chain B","transparency":0.0}],"coordinate_kind":"generated","target_id":"ceacam5-8bw0-a3b3"}},{"campaign_id":"ceacam5-8bw0-multigenerator","arm_id":"pxdesign-proteinmpnn","stage":"smoke","source_candidate_id":"pxdesign-000-proteinmpnn-00","recovery_key":"ceacam5-8bw0-multigenerator/pxdesign-proteinmpnn/smoke/pxdesign-000-proteinmpnn-00","sequence":"SQIDELQAQLQQLQAQLQALVAEAQAAAAAGDKAKLLALLAQTDQLQQQLNQLNQQLVQAKLAA","sequence_length":64,"sequence_sha256":"b35b51b58394aca742cc52fbc6b007dc46becd6b54a1ba309638b32035d7c890","source_manifest_sha256":"20a58ba531e6dd334ae3d8fa10ecbfc86f73cd4c7eb074f923dae39e25857c12","sequence_artifact":{"path":"data/artifacts/binder-candidate-files/fe4efc407c7ffa8441c7-edced5d57f81.fasta","sha256":"edced5d57f81607c26fa2b54f216fda5a9c60a37e2f32706d5d7ee3a248a223d","bytes":94},"design_pose_artifact":{"path":"data/artifacts/binder-candidate-files/fe4efc407c7ffa8441c7-b37beb34cc69.pdb","sha256":"b37beb34cc69cee7a56382116e29badb68cb6250d2bc2f9e78f5c40c0a5e7863","bytes":130231,"original_source_sha256":"f48fdd7750b42edb7de1fbdb17c73ed1e73f2ac9af865d2168e308a847eaeea2","coordinate_records_sha256":"21a16dc8545c8f2ff85564984fe18c629a3e6046c5c14a6058c05b5c3882510f"},"binder_chain_id":"B","observed_protein_chain_lengths":{"A":177,"B":64},"representation":"generated design pose","snapshot":{"path":"data/artifacts/binder-candidate-files/81314eaf77601138822f971c.png","sha256":"81314eaf77601138822f971c90b9b5ff32eeab768646d5a6ec614e9e2015a5ef","title":"CEACAM5 · PXDesign 000 · smoke","caption":"Generated design pose. CEACAM5 target (chain A); binder pxdesign-000-proteinmpnn-00 (chain B). Source status: sequence-designed. Screening state: not run; four-arm join incomplete. Ranking: unranked.","metadata_href":"data/artifacts/binder-candidate-files/81314eaf77601138822f971c.snapshot.json","metadata_sha256":"a4d1102e4c44d866ff7fc29db8cc7d08643cc8c9d55b464f0db42060ffc97161","width":960,"height":720,"coordinate_sources":[{"sha256":"f48fdd7750b42edb7de1fbdb17c73ed1e73f2ac9af865d2168e308a847eaeea2","bytes":130425,"role":"generated-design-pose","object_name":"complex","state":1,"chain_namespace":"author","source_type":"polymer","expected_chains":["A","B"],"original_source_sha256":"f48fdd7750b42edb7de1fbdb17c73ed1e73f2ac9af865d2168e308a847eaeea2","packaged_sha256":"b37beb34cc69cee7a56382116e29badb68cb6250d2bc2f9e78f5c40c0a5e7863","packaged_bytes":130231,"coordinate_href":"data/artifacts/binder-candidate-files/b37beb34cc69cee7a5638211.pdb","removed_contact_metadata_fields":0,"format":"pdb"}],"layers":[{"color":"#17675D","color_mode":"solid","description":"Target chain A; source target geometry present.","name":"target","object_name":"complex","representation":"cartoon","selection":"polymer.protein and chain A","transparency":0.0},{"color":"#526A92","color_mode":"solid","description":"Generated binder chain B.","name":"binder","object_name":"complex","representation":"cartoon","selection":"polymer.protein and chain B","transparency":0.0}],"coordinate_kind":"generated","target_id":"ceacam5-8bw0-a3b3"}},{"campaign_id":"ceacam5-8bw0-multigenerator","arm_id":"pxdesign-proteinmpnn","stage":"scale","source_candidate_id":"pxdesign-000-proteinmpnn-00","recovery_key":"ceacam5-8bw0-multigenerator/pxdesign-proteinmpnn/scale/pxdesign-000-proteinmpnn-00","sequence":"SAAKQAIADLVQQAAALVQAHNDQVKAMIESGTYDPEQLKQLQEQLQAQLAALQAQIDAAKAAA","sequence_length":64,"sequence_sha256":"b27052a7063360ba8a2da4b62d37e8a782f3c3826b7065dff1f3f14fdff2e119","source_manifest_sha256":"b332a91243e635cc40f60393259a43a198d3f9b625f74f081d0ae862da6d42c6","sequence_artifact":{"path":"data/artifacts/binder-candidate-files/4d1682d67b0d85d193e8-2861d62c49bc.fasta","sha256":"2861d62c49bc1080806968cf47309220c16796d5e9a7112d285f5ca5ddfc26fe","bytes":94},"design_pose_artifact":{"path":"data/artifacts/binder-candidate-files/4d1682d67b0d85d193e8-738068413ec8.pdb","sha256":"738068413ec8f8c5da845b8c3791eadc800c5d18c50b40350e0e87354da08caf","bytes":130231,"original_source_sha256":"35d27a471df43f69e27c548c4a266e11c3dd513475dc348c2d5454487a1d3289","coordinate_records_sha256":"4b9274440a0153e584f71c36e69e6abba45af9231c1e831a40d43c0662c3c8de"},"binder_chain_id":"B","observed_protein_chain_lengths":{"A":177,"B":64},"representation":"generated design pose","snapshot":{"path":"data/artifacts/binder-candidate-files/8c03465877810a13afe08832.png","sha256":"8c03465877810a13afe08832cf696d9c7d1b61006644cec382316da9a1c25d6e","title":"CEACAM5 · PXDesign 000 · scale","caption":"Generated design pose. CEACAM5 target (chain A); binder pxdesign-000-proteinmpnn-00 (chain B). Source status: sequence-designed. Screening state: not run; four-arm join incomplete. Ranking: unranked.","metadata_href":"data/artifacts/binder-candidate-files/8c03465877810a13afe08832.snapshot.json","metadata_sha256":"12ceee820d5584246de0c4cf3860a72a544e270967a7e838c88ba67a62f7f5ae","width":960,"height":720,"coordinate_sources":[{"sha256":"35d27a471df43f69e27c548c4a266e11c3dd513475dc348c2d5454487a1d3289","bytes":130425,"role":"generated-design-pose","object_name":"complex","state":1,"chain_namespace":"author","source_type":"polymer","expected_chains":["A","B"],"original_source_sha256":"35d27a471df43f69e27c548c4a266e11c3dd513475dc348c2d5454487a1d3289","packaged_sha256":"738068413ec8f8c5da845b8c3791eadc800c5d18c50b40350e0e87354da08caf","packaged_bytes":130231,"coordinate_href":"data/artifacts/binder-candidate-files/738068413ec8f8c5da845b8c.pdb","removed_contact_metadata_fields":0,"format":"pdb"}],"layers":[{"color":"#17675D","color_mode":"solid","description":"Target chain A; source target geometry present.","name":"target","object_name":"complex","representation":"cartoon","selection":"polymer.protein and chain A","transparency":0.0},{"color":"#526A92","color_mode":"solid","description":"Generated binder chain B.","name":"binder","object_name":"complex","representation":"cartoon","selection":"polymer.protein and chain B","transparency":0.0}],"coordinate_kind":"generated","target_id":"ceacam5-8bw0-a3b3"}},{"campaign_id":"ceacam5-8bw0-multigenerator","arm_id":"pxdesign-proteinmpnn","stage":"scale","source_candidate_id":"pxdesign-001-proteinmpnn-00","recovery_key":"ceacam5-8bw0-multigenerator/pxdesign-proteinmpnn/scale/pxdesign-001-proteinmpnn-00","sequence":"TPEEEELRKLTEESSKFQKEMEEKAREAVENNDMEKYKKINEETKKKLEEMNKKNAEIRAKLAA","sequence_length":64,"sequence_sha256":"6e14cddf2dc1b16095def35925cc6bd00a51174f17e4596200671bd4b0916413","source_manifest_sha256":"b332a91243e635cc40f60393259a43a198d3f9b625f74f081d0ae862da6d42c6","sequence_artifact":{"path":"data/artifacts/binder-candidate-files/310368ce180871be8c0f-749c0cad1709.fasta","sha256":"749c0cad17098c21575553bc70d231657b635cc68d9ff4914fbd8a789d90150e","bytes":94},"design_pose_artifact":{"path":"data/artifacts/binder-candidate-files/310368ce180871be8c0f-4915edf92a1e.pdb","sha256":"4915edf92a1efeadd2b73edf7e0f6ffe49df08835262d848de9d5c0c8f9d6a82","bytes":130231,"original_source_sha256":"0e16974db57d524c3d1405f60c33f4d258a827374a64815ed5372dd01b7409dd","coordinate_records_sha256":"6cb6ba5e00a16d77759c700df34d7d06769a1bd819cea0f52fa34e9d0ad8cb0b"},"binder_chain_id":"B","observed_protein_chain_lengths":{"A":177,"B":64},"representation":"generated design pose","snapshot":{"path":"data/artifacts/binder-candidate-files/7b7d3b1597edbdd7ef0febc7.png","sha256":"7b7d3b1597edbdd7ef0febc709caea248607aadd29681ea77086fa1c54f37385","title":"CEACAM5 · PXDesign 001 · scale","caption":"Generated design pose from the original four-arm campaign. This candidate was later screened in the three-arm checkpoint; the checkpoint failed its control check and no candidate was promoted.","metadata_href":"data/artifacts/binder-candidate-files/7b7d3b1597edbdd7ef0febc7.snapshot.json","metadata_sha256":"888545f3c4a8ea0fc97b9e151c162c16dd9f7da00209ca8e5ff882d2680b1876","width":960,"height":720,"coordinate_sources":[{"sha256":"0e16974db57d524c3d1405f60c33f4d258a827374a64815ed5372dd01b7409dd","bytes":130425,"role":"generated-design-pose","object_name":"complex","state":1,"chain_namespace":"author","source_type":"polymer","expected_chains":["A","B"],"original_source_sha256":"0e16974db57d524c3d1405f60c33f4d258a827374a64815ed5372dd01b7409dd","packaged_sha256":"4915edf92a1efeadd2b73edf7e0f6ffe49df08835262d848de9d5c0c8f9d6a82","packaged_bytes":130231,"coordinate_href":"data/artifacts/binder-candidate-files/4915edf92a1efeadd2b73edf.pdb","removed_contact_metadata_fields":0,"format":"pdb"}],"layers":[{"color":"#17675D","color_mode":"solid","description":"Target chain A; source target geometry present.","name":"target","object_name":"complex","representation":"cartoon","selection":"polymer.protein and chain A","transparency":0.0},{"color":"#526A92","color_mode":"solid","description":"Generated binder chain B.","name":"binder","object_name":"complex","representation":"cartoon","selection":"polymer.protein and chain B","transparency":0.0}],"coordinate_kind":"generated","target_id":"ceacam5-8bw0-a3b3"}},{"campaign_id":"ceacam5-8bw0-replacement-generators-20260904","arm_id":"esmfold2-fast-unconditioned","stage":"smoke","source_candidate_id":"esmfold2-unconditioned-001","recovery_key":"ceacam5-8bw0-replacement-generators-20260904/esmfold2-fast-unconditioned/smoke/esmfold2-unconditioned-001","sequence":"LRSLNIFYVSLTLPPVEQKSFQFGSGRVLWFFPDGDKLIVKDMNHDTMRRPGHMDDATSEPYIK","sequence_length":64,"sequence_sha256":"32e9f4fba2f34565443d17a74790b7d21d1d2a9807a9ac717e4104d2f58abe7d","source_manifest_sha256":"c6cfc85ff4d4cafcfca8aeab8b3064f882cf6cbda91940b2921082292fe88652","sequence_artifact":{"path":"data/artifacts/binder-candidate-files/78136856738a615a8eef-fd3d26bf59bb.fasta","sha256":"fd3d26bf59bbae76736813b3e34a0f0f6dfd96d6e3ebfe7841f148d4575d42a4","bytes":93},"design_pose_artifact":{"path":"data/artifacts/binder-candidate-files/78136856738a615a8eef-1122412e0189.pdb","sha256":"1122412e01897edc09751158d332caf65bb72b25374acc6f8ed38f6325d24933","bytes":151630,"original_source_sha256":"1122412e01897edc09751158d332caf65bb72b25374acc6f8ed38f6325d24933","coordinate_records_sha256":"1122412e01897edc09751158d332caf65bb72b25374acc6f8ed38f6325d24933"},"binder_chain_id":"B","observed_protein_chain_lengths":{"A":177,"B":64},"representation":"generated design pose","snapshot":{"path":"data/artifacts/binder-candidate-files/c4c00ae4649641007fd56f71.png","sha256":"c4c00ae4649641007fd56f7133596e50da1add95ae2f939c4a0fb0b80374779a","title":"ESMFold2 · sequence 001","caption":"Predicted fold of the generated sequence (chain B). The ESMFold2 request included the target sequence but did not specify a binding site. The candidate chain is shown in isolation.","metadata_href":"data/artifacts/binder-candidate-files/c4c00ae4649641007fd56f71.snapshot.json","metadata_sha256":"d01973da9cb27f3305d14a96781476e93096b4d720fc794f99b0acda8517d00f","width":960,"height":720,"coordinate_sources":[{"sha256":"1122412e01897edc09751158d332caf65bb72b25374acc6f8ed38f6325d24933","bytes":151630,"role":"generated-design-pose","object_name":"complex","state":1,"chain_namespace":"author","source_type":"polymer","expected_chains":["A","B"],"original_source_sha256":"1122412e01897edc09751158d332caf65bb72b25374acc6f8ed38f6325d24933","packaged_sha256":"1122412e01897edc09751158d332caf65bb72b25374acc6f8ed38f6325d24933","packaged_bytes":151630,"coordinate_href":"data/artifacts/binder-candidate-files/1122412e01897edc09751158.pdb","removed_contact_metadata_fields":0,"format":"pdb"}],"layers":[{"color":"#526A92","color_mode":"solid","description":"Generated sequence · chain B","name":"binder","object_name":"complex","representation":"cartoon","selection":"polymer.protein and chain B","transparency":0.0}],"coordinate_kind":"predicted","target_id":"T-ENSG00000105388"}},{"campaign_id":"ceacam5-8bw0-replacement-generators-20260904","arm_id":"esmfold2-fast-unconditioned","stage":"scale","source_candidate_id":"esmfold2-unconditioned-002","recovery_key":"ceacam5-8bw0-replacement-generators-20260904/esmfold2-fast-unconditioned/scale/esmfold2-unconditioned-002","sequence":"RKEKKLFIALQQHDAKPVPDPPERNFITSSKTQGPNNDDLMEFRGELHLKYVMQIYHRSWEALS","sequence_length":64,"sequence_sha256":"15ce01b4c21a6b6745a4dbf4e358d7cf99b4883ce7042419cef3d3e2e99b8a6d","source_manifest_sha256":"c6cfc85ff4d4cafcfca8aeab8b3064f882cf6cbda91940b2921082292fe88652","sequence_artifact":{"path":"data/artifacts/binder-candidate-files/9b6d2507ce91834a6367-d6e9d059cc33.fasta","sha256":"d6e9d059cc33a861cc3585c1943884e02a233d32672d9bab289c495dd1ff82f8","bytes":93},"design_pose_artifact":{"path":"data/artifacts/binder-candidate-files/9b6d2507ce91834a6367-80a72746911d.pdb","sha256":"80a72746911d491a0051d9ec08febc959098335e772ae15b350ca1ffe849e926","bytes":152440,"original_source_sha256":"80a72746911d491a0051d9ec08febc959098335e772ae15b350ca1ffe849e926","coordinate_records_sha256":"80a72746911d491a0051d9ec08febc959098335e772ae15b350ca1ffe849e926"},"binder_chain_id":"B","observed_protein_chain_lengths":{"A":177,"B":64},"representation":"generated design pose","snapshot":{"path":"data/artifacts/binder-candidate-files/e83244f948ed60ae5c3fbf71.png","sha256":"e83244f948ed60ae5c3fbf713a098ad066c6c8097ca67a1cffb8a250dd343500","title":"ESMFold2 · sequence 002","caption":"Predicted fold of the generated sequence (chain B). The ESMFold2 request included the target sequence but did not specify a binding site. The candidate chain is shown in isolation.","metadata_href":"data/artifacts/binder-candidate-files/e83244f948ed60ae5c3fbf71.snapshot.json","metadata_sha256":"a3dae3b3a3df34e5f06d171c5256ec5caba5c95e8897f8ff870e2af122b6f5aa","width":960,"height":720,"coordinate_sources":[{"sha256":"80a72746911d491a0051d9ec08febc959098335e772ae15b350ca1ffe849e926","bytes":152440,"role":"generated-design-pose","object_name":"complex","state":1,"chain_namespace":"author","source_type":"polymer","expected_chains":["A","B"],"original_source_sha256":"80a72746911d491a0051d9ec08febc959098335e772ae15b350ca1ffe849e926","packaged_sha256":"80a72746911d491a0051d9ec08febc959098335e772ae15b350ca1ffe849e926","packaged_bytes":152440,"coordinate_href":"data/artifacts/binder-candidate-files/80a72746911d491a0051d9ec.pdb","removed_contact_metadata_fields":0,"format":"pdb"}],"layers":[{"color":"#526A92","color_mode":"solid","description":"Generated sequence · chain B","name":"binder","object_name":"complex","representation":"cartoon","selection":"polymer.protein and chain B","transparency":0.0}],"coordinate_kind":"predicted","target_id":"T-ENSG00000105388"}},{"campaign_id":"ceacam5-8bw0-replacement-generators-20260904","arm_id":"esmfold2-fast-unconditioned","stage":"scale","source_candidate_id":"esmfold2-unconditioned-003","recovery_key":"ceacam5-8bw0-replacement-generators-20260904/esmfold2-fast-unconditioned/scale/esmfold2-unconditioned-003","sequence":"MSDVRMADPSRRTFLDIMAYLEYRLAMFLEWLMPPGSPDSNHGEDHRFMEDQLDWNADGGGHNS","sequence_length":64,"sequence_sha256":"325ae69ed9e8cd72f1e16ac656d14cbac3b027963a558e6f66e8ec2b7741cc7d","source_manifest_sha256":"c6cfc85ff4d4cafcfca8aeab8b3064f882cf6cbda91940b2921082292fe88652","sequence_artifact":{"path":"data/artifacts/binder-candidate-files/1d8e773809c110f56361-43fdb8f34d5d.fasta","sha256":"43fdb8f34d5dc84ceae01d7e5bc1899c5efa08badfb95fd9881245e0ef55af19","bytes":93},"design_pose_artifact":{"path":"data/artifacts/binder-candidate-files/1d8e773809c110f56361-b9c391ed3513.pdb","sha256":"b9c391ed3513b318caf321bbdeb2c6f261cd601ced46d7429664540563a9b1f3","bytes":151225,"original_source_sha256":"b9c391ed3513b318caf321bbdeb2c6f261cd601ced46d7429664540563a9b1f3","coordinate_records_sha256":"b9c391ed3513b318caf321bbdeb2c6f261cd601ced46d7429664540563a9b1f3"},"binder_chain_id":"B","observed_protein_chain_lengths":{"A":177,"B":64},"representation":"generated design pose","snapshot":{"path":"data/artifacts/binder-candidate-files/fbefdd42348eb6b313f98d5c.png","sha256":"fbefdd42348eb6b313f98d5c1b4aa53422ffc9a21fa0710f5931ac086da3571c","title":"ESMFold2 · sequence 003","caption":"Predicted fold of the generated sequence (chain B). The ESMFold2 request included the target sequence but did not specify a binding site. The candidate chain is shown in isolation.","metadata_href":"data/artifacts/binder-candidate-files/fbefdd42348eb6b313f98d5c.snapshot.json","metadata_sha256":"b5d6f932598bb2b2a9fcd85dfec37fc3892ef25934dffa6c8fb9a97935021637","width":960,"height":720,"coordinate_sources":[{"sha256":"b9c391ed3513b318caf321bbdeb2c6f261cd601ced46d7429664540563a9b1f3","bytes":151225,"role":"generated-design-pose","object_name":"complex","state":1,"chain_namespace":"author","source_type":"polymer","expected_chains":["A","B"],"original_source_sha256":"b9c391ed3513b318caf321bbdeb2c6f261cd601ced46d7429664540563a9b1f3","packaged_sha256":"b9c391ed3513b318caf321bbdeb2c6f261cd601ced46d7429664540563a9b1f3","packaged_bytes":151225,"coordinate_href":"data/artifacts/binder-candidate-files/b9c391ed3513b318caf321bb.pdb","removed_contact_metadata_fields":0,"format":"pdb"}],"layers":[{"color":"#526A92","color_mode":"solid","description":"Generated sequence · chain B","name":"binder","object_name":"complex","representation":"cartoon","selection":"polymer.protein and chain B","transparency":0.0}],"coordinate_kind":"predicted","target_id":"T-ENSG00000105388"}}],"scope":"Exact candidate sequences and generated design-pose files; independent of campaign outcome summaries.","source_inventory_sha256":["23e58c5bc862ecff390d712806af6aabd8a86167d3f8b48ff6c44f8d208e298a","c27d3c640829d42fe666a8c6a30dd0b448892d86bc36cba5788a9ba65294565e"]}
