{"campaign_id":"ceacam5-8bw0-paired-fv-context-diagnostic","claim_ceiling":"paired-variable-domain-context-control-diagnostic","handoff_id":"H-CEACAM5-8BW0-PAIRED-FV-DIAGNOSTIC","kind":"paired-control-diagnostic","payload":{"campaign_id":"ceacam5-8bw0-paired-fv-context-diagnostic","claim_ceiling":"paired-variable-domain-context-control-diagnostic","completed_checkpoint_relationship":"none; the existing three-arm checkpoint was not modified or reinterpreted","display_title":"Paired-variable-domain control diagnostic","executed_at":"2026-09-04","execution":{"completed_control":"positive","completed_predictions":1,"completed_seed":20260931,"issued_predictions":1},"projection_note":"Source hashes identify the original input records.","provider_free_paired_group_measurement":{"full_footprint_contact_count":12,"full_footprint_residue_count":17,"group_ipsae_min":0.0,"interpretation":"One positive observation cannot evaluate a six-observation paired-control panel. It does not support an inference about paired versus single-variable-domain context.","state":"measured-single-positive-only","target_alignment_rmsd_angstrom":2.1726},"qualification":{"failed_gate_assessment":"not-run","generated_candidates":0,"promotions":0,"qualified":false,"state":"not-evaluable-incomplete-panel"},"schema_version":"codex-surface-reader-control-diagnostic/v1","show":["The construct is paired VH+VL/Fv-like context: A=CEACAM5 177 aa, B=VH 117 aa, C=VL 104 aa.","One structure prediction completed, with four verified structure and confidence files.","A separate provider-free union(B,C) measurement on that observation returned group iPSAE-min 0.0, 12 of 17 deposited footprint residues contacted, and target RMSD 2.1726 Å.","The full two-control, three-seed panel is incomplete and was not qualified.","No generated candidates were included or promoted."],"source_references":[{"role":"report-handoff","sha256":"72f9d08fc68ec10f46440638ccffdb5b84e44e7b42504375496171e05fef02c2","verification":"hash computed from selected source bytes"},{"role":"diagnostic-outcome","sha256":"c0cff32084c2f5a030bdda3dfc89afe9b8fb7dad1a0f96816bca1643b1f0f860","verification":"hash computed from selected source bytes"},{"role":"diagnostic-plan","sha256":"be3b63444df4f9b6f1967c087cd3f0cff2a6baa6a13678e9ed4faeb2a0ee28c5","verification":"hash declared by outcome; artifact not read for this projection"},{"role":"complex-pdb","sha256":"3f188d647fadc176a3445151ec0e0a7821bf2f6b92dd92546ba2e05275cf12e4","verification":"hash declared by outcome; artifact not read for this projection"},{"role":"pae-json","sha256":"98b8517022d6ecc5e9e54660069dffa46ba430da9d55f14ab099eebc57e72a04","verification":"hash declared by outcome; artifact not read for this projection"},{"role":"paired-group-measurement","sha256":"77b9b238c69ec8d6fe6da7b0bfb8f5cd46105b09f971f6354f0ab5983228b1c6","verification":"hash declared by outcome; artifact not read for this projection"}],"state":"executed-stop-local-scorer-contract-incompatibility","status_label":"Stopped after 1 of 6 predictions","summary":"The deposited CEACAM5 + VH + VL positive prediction completed, but a local scorer-contract incompatibility triggered the prospective stop rule before the negative or replicate predictions were issued."},"schema_version":"surface-report-campaign-handoff/v1"}