Surface AtlasMucinous colon cancer

CCR9

C-C chemokine receptor type 9. UniProt annotates extracellular residues 1–48, 110–120, 186–208, 284–290.

Sequence and protein regions

Explore the CCR9 sequence, select annotated regions, and copy a request to continue in Codex.

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RNA expression in tumor samples

Median CCR9 RNA expression by tumor type, measured in RSEM units. The study selected these samples using microsatellite-stability score thresholds.

Mucinous tumors37 samples1.9
Other tumor types438 samples1.9
Compare the sample groups · cBioPortal measurements (JSON)

Sequence & binding sites

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Sequence annotations and source records

Canonical sequence and topology

Target ID
T-ENSG00000173585
UniProt accession
P51686
Sequence state
available
Canonical sequence
Yes
Length in amino acids
369
Sequence SHA-256
8fd6cd6e21332287f6b23e7564a64a9a42480cfcdd689e963e17997b806d1660
View and select the full canonical sequence
Sequence positions 1–369

Gray shows the full canonical sequence. Colored spans mark the listed intervals.

Membrane-spanning segments
49–74: Helical; Name=186–109: Helical; Name=2121–150: Helical; Name=3160–185: Helical; Name=4209–243: Helical; Name=5249–283: Helical; Name=6291–321: Helical; Name=7
49–74 (Helical; Name=1); 86–109 (Helical; Name=2); 121–150 (Helical; Name=3); 160–185 (Helical; Name=4); 209–243 (Helical; Name=5); 249–283 (Helical; Name=6); 291–321 (Helical; Name=7)
Source-annotated domains
1–48: Extracellular75–85: Cytoplasmic110–120: Extracellular151–159: Cytoplasmic186–208: Extracellular244–248: Cytoplasmic284–290: Extracellular322–369: Cytoplasmic
1–48 (Extracellular); 75–85 (Cytoplasmic); 110–120 (Extracellular); 151–159 (Cytoplasmic); 186–208 (Extracellular); 244–248 (Cytoplasmic); 284–290 (Extracellular); 322–369 (Cytoplasmic)
Source-annotated extracellular intervals
1–48110–120186–208284–290
1–48; 110–120; 186–208; 284–290

UniProt annotates the following extracellular intervals.

One-based positions include both interval endpoints.
StartEndLengthSequence and source
14848
Sequence and source
Basis
reviewed-uniprot-topological-domain
Evidence class
source-annotated-topology
Sequence SHA-256
a237935c544453d2c7426aab520a4969432aa909a9bf03b1cab2e93feb272f14
11012011
Sequence and source
Basis
reviewed-uniprot-topological-domain
Evidence class
source-annotated-topology
Sequence SHA-256
f18bc40cc42b295499b4c2897e3a969f0e0999b9ba091c95129358dcb6574052
18620823
Sequence and source
Basis
reviewed-uniprot-topological-domain
Evidence class
source-annotated-topology
Sequence SHA-256
d8e5d10444f1671eb18c73a38c0893839ba40cceca7e1f2344e3d37cd1974d63
2842907
Sequence and source
Basis
reviewed-uniprot-topological-domain
Evidence class
source-annotated-topology
Sequence SHA-256
d65c2e42a9895f6e4820346767409f9325cf5e833f4525ffc8041d350f2ff3e4
Sequence and topology sources
Source role
canonical-sequence
Source
alphafold-db-canonical-uniprot-field
Extracted field
uniprotSequence
Source row accession
Not recorded

Download source snapshot

Open sequence source
Source role
reviewed-topology
Source
UniProt reviewed human surface-field snapshot
Extracted field
Not recorded
Source row accession
P51686

Download source snapshot (gzip)

subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000305|PubMed:27926729}; Multi-pass membrane protein {ECO:0000305|PubMed:27926729}.
transmembrane
TRANSMEM 49..74; /note="Helical; Name=1"; /evidence="ECO:0000269|PubMed:27926729"; TRANSMEM 86..109; /note="Helical; Name=2"; /evidence="ECO:0000269|PubMed:27926729"; TRANSMEM 121..150; /note="Helical; Name=3"; /evidence="ECO:0000269|PubMed:27926729"; TRANSMEM 160..185; /note="Helical; Name=4"; /evidence="ECO:0000269|PubMed:27926729"; TRANSMEM 209..243; /note="Helical; Name=5"; /evidence="ECO:0000269|PubMed:27926729"; TRANSMEM 249..283; /note="Helical; Name=6"; /evidence="ECO:0000269|PubMed:27926729"; TRANSMEM 291..321; /note="Helical; Name=7"; /evidence="ECO:0000269|PubMed:27926729"
topological_domain
TOPO_DOM 1..48; /note="Extracellular"; /evidence="ECO:0000269|PubMed:27926729"; TOPO_DOM 75..85; /note="Cytoplasmic"; /evidence="ECO:0000269|PubMed:27926729"; TOPO_DOM 110..120; /note="Extracellular"; /evidence="ECO:0000269|PubMed:27926729"; TOPO_DOM 151..159; /note="Cytoplasmic"; /evidence="ECO:0000269|PubMed:27926729"; TOPO_DOM 186..208; /note="Extracellular"; /evidence="ECO:0000269|PubMed:27926729"; TOPO_DOM 244..248; /note="Cytoplasmic"; /evidence="ECO:0000269|PubMed:27926729"; TOPO_DOM 284..290; /note="Extracellular"; /evidence="ECO:0000269|PubMed:27926729"; TOPO_DOM 322..369; /note="Cytoplasmic"; /evidence="ECO:0000255, ECO:0000269|PubMed:27926729"
signal_peptide
Not recorded
lipidation
Not recorded

Download all canonical target sequences (FASTA)

Protein identity and location

Protein
C-C chemokine receptor type 9
Protein location
Transmembrane protein
Canonical sequence
P51686 · 369 amino acids
Extracellular region
UniProt annotates extracellular residues 1–48, 110–120, 186–208, 284–290.

Expression in normal tissues

RNA specificity
Tissue enriched
RNA distribution
Detected in some
RNA tissue-specific nTPM
lymphoid tissue: 120.8
Protein specificity
Not detected
Protein distribution
Not detected
Immunohistochemistry reliability
Uncertain
Immunofluorescence reliability
Approved
Subcellular location
Plasma membrane

Sources and downloads

UniProt protein recordTarget measurements (JSON)Sequence annotations (JSON)Target sequences (FASTA)

CCR9 · ENSG00000173585 · P51686

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