Surface AtlasMucinous colon cancer

OR4M1

Olfactory receptor 4M1. UniProt annotates extracellular residues 1–25, 80–100, 159–195, 261–271.

Sequence and protein regions

Explore the OR4M1 sequence, select annotated regions, and copy a request to continue in Codex.

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RNA expression in tumor samples

Median OR4M1 RNA expression by tumor type, measured in RSEM units. The study selected these samples using microsatellite-stability score thresholds.

Mucinous tumors23 samples0.0
Other tumor types258 samples0.0
Compare the sample groups · cBioPortal measurements (JSON)

Sequence & binding sites

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Sequence annotations and source records

Canonical sequence and topology

Target ID
T-ENSG00000176299
UniProt accession
Q8NGD0
Sequence state
available
Canonical sequence
Yes
Length in amino acids
313
Sequence SHA-256
4a399e4ae20c6ba514d8857c532cce00298ee2d377c85fc6d0fa2a8259910003
View and select the full canonical sequence
Sequence positions 1–313

Gray shows the full canonical sequence. Colored spans mark the listed intervals.

Membrane-spanning segments
26–49: Helical; Name=158–79: Helical; Name=2101–120: Helical; Name=3140–158: Helical; Name=4196–219: Helical; Name=5238–260: Helical; Name=6272–291: Helical; Name=7
26–49 (Helical; Name=1); 58–79 (Helical; Name=2); 101–120 (Helical; Name=3); 140–158 (Helical; Name=4); 196–219 (Helical; Name=5); 238–260 (Helical; Name=6); 272–291 (Helical; Name=7)
Source-annotated domains
1–25: Extracellular50–57: Cytoplasmic80–100: Extracellular121–139: Cytoplasmic159–195: Extracellular220–237: Cytoplasmic261–271: Extracellular292–313: Cytoplasmic
1–25 (Extracellular); 50–57 (Cytoplasmic); 80–100 (Extracellular); 121–139 (Cytoplasmic); 159–195 (Extracellular); 220–237 (Cytoplasmic); 261–271 (Extracellular); 292–313 (Cytoplasmic)
Source-annotated extracellular intervals
1–2580–100159–195261–271
1–25; 80–100; 159–195; 261–271

UniProt annotates the following extracellular intervals.

One-based positions include both interval endpoints.
StartEndLengthSequence and source
12525
Sequence and source
Basis
reviewed-uniprot-topological-domain
Evidence class
source-annotated-topology
Sequence SHA-256
f8349260851171cde9c7af8be74a63b2e4417026f9c26c08fc5af78b8b252f41
8010021
Sequence and source
Basis
reviewed-uniprot-topological-domain
Evidence class
source-annotated-topology
Sequence SHA-256
d0a96a2039ce05593c97b41bc46769e97b955dd1866dd208c4220b4d3891f72e
15919537
Sequence and source
Basis
reviewed-uniprot-topological-domain
Evidence class
source-annotated-topology
Sequence SHA-256
6f177c948fdbe514657514120c5db278564b691861cc3630d9e6d087bfab1bea
26127111
Sequence and source
Basis
reviewed-uniprot-topological-domain
Evidence class
source-annotated-topology
Sequence SHA-256
5fa1488ade8febf33ff96f2588a47dff2f8212a038de5e7b0324ae7884f66b0d
Sequence and topology sources
Source role
canonical-sequence
Source
alphafold-db-canonical-uniprot-field
Extracted field
uniprotSequence
Source row accession
Not recorded

Download source snapshot

Open sequence source
Source role
reviewed-topology
Source
UniProt reviewed human surface-field snapshot
Extracted field
Not recorded
Source row accession
Q8NGD0

Download source snapshot (gzip)

subcellular_location
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:31230984}; Multi-pass membrane protein {ECO:0000255|RuleBase:RU363047}.
transmembrane
TRANSMEM 26..49; /note="Helical; Name=1"; /evidence="ECO:0000255"; TRANSMEM 58..79; /note="Helical; Name=2"; /evidence="ECO:0000255"; TRANSMEM 101..120; /note="Helical; Name=3"; /evidence="ECO:0000255"; TRANSMEM 140..158; /note="Helical; Name=4"; /evidence="ECO:0000255"; TRANSMEM 196..219; /note="Helical; Name=5"; /evidence="ECO:0000255"; TRANSMEM 238..260; /note="Helical; Name=6"; /evidence="ECO:0000255"; TRANSMEM 272..291; /note="Helical; Name=7"; /evidence="ECO:0000255"
topological_domain
TOPO_DOM 1..25; /note="Extracellular"; /evidence="ECO:0000255"; TOPO_DOM 50..57; /note="Cytoplasmic"; /evidence="ECO:0000255"; TOPO_DOM 80..100; /note="Extracellular"; /evidence="ECO:0000255"; TOPO_DOM 121..139; /note="Cytoplasmic"; /evidence="ECO:0000255"; TOPO_DOM 159..195; /note="Extracellular"; /evidence="ECO:0000255"; TOPO_DOM 220..237; /note="Cytoplasmic"; /evidence="ECO:0000255"; TOPO_DOM 261..271; /note="Extracellular"; /evidence="ECO:0000255"; TOPO_DOM 292..313; /note="Cytoplasmic"; /evidence="ECO:0000255"
signal_peptide
Not recorded
lipidation
Not recorded

Download all canonical target sequences (FASTA)

Protein identity and location

Protein
Olfactory receptor 4M1
Protein location
Transmembrane protein
Canonical sequence
Q8NGD0 · 313 amino acids
Extracellular region
UniProt annotates extracellular residues 1–25, 80–100, 159–195, 261–271.

Expression in normal tissues

RNA specificity
Not detected
RNA distribution
Not detected
Protein specificity
Not detected
Protein distribution
Not detected
Immunohistochemistry reliability
Uncertain

Sources and downloads

UniProt protein recordTarget measurements (JSON)Sequence annotations (JSON)Target sequences (FASTA)

OR4M1 · ENSG00000176299 · Q8NGD0

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