SLC27A5

Long-chain fatty acid transport protein 5. The canonical sequence contains 690 amino acids.

Sequence and protein regions

Explore the SLC27A5 sequence, select annotated regions, and copy a request to continue in Codex.

RNA expression in tumor samples

Median SLC27A5 RNA expression by tumor type, measured in RSEM units. The study selected these samples using microsatellite-stability score thresholds.

Mucinous tumors37 samples145.0

Other tumor types438 samples138.2

Compare the sample groups · cBioPortal measurements (JSON)

Sequence & binding sites

Choose a protein region, search amino-acid letters, or inspect a recorded binding site.

Loading sequence…

Open the sequence explorer

Sequence annotations and source records

Canonical sequence and topology

Target ID: T-ENSG00000083807
UniProt accession: Q9Y2P5
Sequence state: available
Canonical sequence: Yes
Length in amino acids: 690
Sequence SHA-256: 8d7d28e32b0e3203deb55f7ad05e3c7011f917935385a100c702f13c4beab68c

View and select the full canonical sequence

Canonical amino-acid sequence

MGVRQQLALLLLLLLLLWGLGQPVWPVAVALTLRWLLGDPTCCVLLGLAMLARPWLGPWVPHGLSLAAAALALTLLPARLPPGLRWLPADVIFLAKILHLGLKIRGCLSRQPPDTFVDAFERRARAQPGRALLVWTGPGAGSVTFGELDARACQAAWALKAELGDPASLCAGEPTALLVLASQAVPALCMWLGLAKLGCPTAWINPHGRGMPLAHSVLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTSPTPGVGALGAALDAAPSHPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVLQMSKMLSLSGATADDVVYTVLPLYHVMGLVVGILGCLDLGATCVLAPKFSTSCFWDDCRQHGVTVILYVGELLRYLCNIPQQPEDRTHTVRLAMGNGLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVGRCGALGKMSCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQPFVGYRGPRELSERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEKLYQHVRAWLPAYATPHFIRIQDAMEVTSTFKLMKTRLVREGFNVGIVVDPLFVLDNRAQSFRPLTAEMYQAVCEGTWRL

Sequence positions 1–690

Gray shows the full canonical sequence. Colored spans mark the listed intervals.

Membrane-spanning segments

31–51 (Helical); 56–76 (Helical)

Source-annotated domains

1–30 (Cytoplasmic); 77–690 (Cytoplasmic)

This collection has no explicit extracellular interval for this protein.

Sequence and topology sources

Source role: canonical-sequence
Source: alphafold-db-canonical-uniprot-field
Extracted field: uniprotSequence
Source row accession: Not recorded

Download source snapshot

Open sequence source

Source role: reviewed-topology
Source: UniProt reviewed human surface-field snapshot
Extracted field: Not recorded
Source row accession: Q9Y2P5

Download source snapshot (gzip)

subcellular_location: SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:10479480}; Multi-pass membrane protein {ECO:0000255}. Microsome {ECO:0000250|UniProtKB:Q9ES38}. Cell membrane {ECO:0000250|UniProtKB:Q4LDG0}; Multi-pass membrane protein {ECO:0000255}.
transmembrane: TRANSMEM 31..51; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 56..76; /note="Helical"; /evidence="ECO:0000255"
topological_domain: TOPO_DOM 1..30; /note="Cytoplasmic"; /evidence="ECO:0000305|PubMed:11980911"; TOPO_DOM 77..690; /note="Cytoplasmic"; /evidence="ECO:0000305|PubMed:11980911"
signal_peptide: Not recorded
lipidation: Not recorded

Download all canonical target sequences (FASTA)

Protein identity and location

Protein: Long-chain fatty acid transport protein 5
Protein location: Transmembrane protein
Canonical sequence: Q9Y2P5 · 690 amino acids

Expression in normal tissues

RNA specificity: Tissue enriched
RNA distribution: Detected in all
RNA tissue-specific nTPM: liver: 989.3
Protein specificity: Group enriched
Protein distribution: Detected in many
Immunohistochemistry reliability: Enhanced
Protein tissue-specific intensity: bone marrow: 59,066,437.5; fallopian tube: 21,506,468.3; intestine: 35,729,409.3; liver: 81,842,804.1
Tissue cell-type enrichment: Breast - Breast glandular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids

Human Protein Atlas: SLC27A5

Sources and downloads

UniProt protein record Target measurements (JSON)Sequence annotations (JSON)Target sequences (FASTA)

SLC27A5 · ENSG00000083807 · Q9Y2P5