SLC38A11

Putative sodium-coupled neutral amino acid transporter 11. The canonical sequence contains 406 amino acids.

Sequence and protein regions

Explore the SLC38A11 sequence, select annotated regions, and copy a request to continue in Codex.

RNA expression in tumor samples

Median SLC38A11 RNA expression by tumor type, measured in RSEM units. The study selected these samples using microsatellite-stability score thresholds.

Mucinous tumors37 samples2.4

Other tumor types438 samples5.8

Compare the sample groups · cBioPortal measurements (JSON)

Sequence & binding sites

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Sequence annotations and source records

Canonical sequence and topology

Target ID: T-ENSG00000169507
UniProt accession: Q08AI6
Sequence state: available
Canonical sequence: Yes
Length in amino acids: 406
Sequence SHA-256: 5edf4d89a116167cddf8becfae7b9a4ca6897ebe5b11fe5224a2565003f77d53

View and select the full canonical sequence

Canonical amino-acid sequence

MKQAGFPLGILLLFWVSYVTDFSLVLLIKGGALSGTDTYQSLVNKTFGFPGYLLLSVLQFLYPFIAMISYNIIAGDTLSKVFQRIPGVDPENVFIGRHFIIGLSTVTFTLPLSLYRNIAKLGKVSLISTGLTTLILGIVMARAISLGPHIPKTEDAWVFAKPNAIQAVGVMSFAFICHHNSFLVYSSLEEPTVAKWSRLIHMSIVISVFICIFFATCGYLTFTGFTQGDLFENYCRNDDLVTFGRFCYGVTVILTYPMECFVTREVIANVFFGGNLSSVFHIVVTVMVITVATLVSLLIDCLGIVLELNGVLCATPLIFIIPSACYLKLSEEPRTHSDKIMSCVMLPIGAVVMVFGFVMAITNTQDCTHGQEMFYCFPDNFSLTNTSESHVQQTTQLSTLNISIFQ

Sequence positions 1–406

Gray shows the full canonical sequence. Colored spans mark the listed intervals.

Membrane-spanning segments

8–28 (Helical); 48–68 (Helical); 93–113 (Helical); 121–141 (Helical); 156–176 (Helical); 202–222 (Helical); 241–263 (Helical); 279–299 (Helical); 301–321 (Helical); 340–360 (Helical)

Source-annotated domains

1–7 (Cytoplasmic)

This collection has no explicit extracellular interval for this protein.

Sequence and topology sources

Source role: canonical-sequence
Source: alphafold-db-canonical-uniprot-field
Extracted field: uniprotSequence
Source row accession: Not recorded

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Open sequence source

Source role: reviewed-topology
Source: UniProt reviewed human surface-field snapshot
Extracted field: Not recorded
Source row accession: Q08AI6

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subcellular_location: SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
transmembrane: TRANSMEM 8..28; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 48..68; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 93..113; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 121..141; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 156..176; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 202..222; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 241..263; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 279..299; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 301..321; /note="Helical"; /evidence="ECO:0000255"; TRANSMEM 340..360; /note="Helical"; /evidence="ECO:0000255"
topological_domain: TOPO_DOM 1..7; /note="Cytoplasmic"; /evidence="ECO:0000255"
signal_peptide: Not recorded
lipidation: Not recorded

Download all canonical target sequences (FASTA)

Protein identity and location

Protein: Putative sodium-coupled neutral amino acid transporter 11
Protein location: Transmembrane protein
Canonical sequence: Q08AI6 · 406 amino acids

Expression in normal tissues

RNA specificity: Tissue enhanced
RNA distribution: Detected in many
RNA tissue-specific nTPM: choroid plexus: 24.4; epididymis: 30.4
Protein specificity: Not detected
Protein distribution: Not detected
Immunohistochemistry reliability: Uncertain
Tissue cell-type enrichment: Adrenal gland - Adrenal medulla cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Spleen - B-cells (Spleen)

Human Protein Atlas: SLC38A11

Sources and downloads

UniProt protein record Target measurements (JSON)Sequence annotations (JSON)Target sequences (FASTA)

SLC38A11 · ENSG00000169507 · Q08AI6